Bhadange Yogesh A, Carpenter Jitendra, Saharan Virendra Kumar
Department of Chemical Engineering, Malaviya National Institute of Technology, Jaipur 302017, India.
Department of Chemical Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education (MAHE), Manipal 576104, India.
ACS Omega. 2024 Jul 8;9(29):31274-31297. doi: 10.1021/acsomega.4c02718. eCollection 2024 Jul 23.
The extraction of bioactive components from natural sources has gained significant attention in recent years due to increasing demand for natural and functional constituents in various industries, including pharmaceuticals, food, and cosmetics. This review paper aims to provide a comprehensive overview of the studies on extracting bioactive components from natural sources using different advanced extraction techniques. It highlights the need for efficient extraction methods to preserve these components' integrity and bioactivity. Various extraction techniques as supercritical-fluid extraction, microwave-assisted extraction, ultrasound-assisted extraction, subcritical solvent extraction, and solid-phase microextraction are explored in detail, highlighting their principles, advantages, and limitations. The review further examines the impact of different factors on the extraction process, including solvent selection, extraction time, temperature, ultrasonication-amplitude, etc. Additionally, emerging techniques, such as green extraction methods and nanotechnology-based approaches, are discussed, emphasizing their potential to enhance the extraction efficiency and sustainability of the process. Furthermore, the review presents case studies and experimental results from recent research articles, providing insights into applying different extraction techniques for specific bioactive components, such as phenolics, flavonoids, alkaloids, and essential oils. It discusses the extraction yield, bioactivity, and potential utilization of the extracted components in various industries. Overall, this review paper is valuable for researchers, scientists, and industry professionals interested in extracting bioactive components from natural sources. It consolidates the current knowledge on different advanced extraction techniques, their optimization parameters, and their potential applications, facilitating further advancements in the field and the development of innovative extraction methods for bioactive component extraction from natural sources.
近年来，由于制药、食品和化妆品等各个行业对天然和功能性成分的需求不断增加，从天然来源中提取生物活性成分受到了广泛关注。这篇综述文章旨在全面概述使用不同先进提取技术从天然来源中提取生物活性成分的研究。它强调了需要高效的提取方法来保持这些成分的完整性和生物活性。详细探讨了各种提取技术，如超临界流体萃取、微波辅助萃取、超声辅助萃取、亚临界溶剂萃取和固相微萃取，突出了它们的原理、优点和局限性。该综述进一步研究了不同因素对提取过程的影响，包括溶剂选择、提取时间、温度、超声振幅等。此外，还讨论了新兴技术，如绿色提取方法和基于纳米技术的方法，强调了它们提高提取效率和过程可持续性的潜力。此外，该综述还展示了近期研究文章的案例研究和实验结果，深入了解了针对特定生物活性成分（如酚类、黄酮类、生物碱和精油）应用不同提取技术的情况。它讨论了提取产率、生物活性以及提取成分在各个行业中的潜在用途。总体而言，这篇综述文章对有兴趣从天然来源中提取生物活性成分的研究人员、科学家和行业专业人士具有重要价值。它整合了关于不同先进提取技术、其优化参数及其潜在应用的当前知识，促进了该领域的进一步发展以及开发从天然来源中提取生物活性成分的创新提取方法。
