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桔梗根中桔梗皂苷的生物转化及药理活性

Biotransformation and pharmacological activities of platycosides from roots.

作者信息

Shi Lin, Cui Tong, Wang Xinyue, Wu Rina, Wu Junrui, Wang Yanqun, Wang Weiming

机构信息

College of Food Science, Shenyang Agricultural University, Shenyang 110866, China.

Institute of Chinese Materia Medica, Heilongjiang Academy of Chinese Medicine Sciences, Harbin 150036, China.

出版信息

Chin Herb Med. 2024 Apr 30;16(3):392-400. doi: 10.1016/j.chmed.2024.01.004. eCollection 2024 Jul.

Abstract

In Northeast China, Goubao pickle is a popular food fermented from the roots of as the main material, offering a unique flavor and rich nutritional value. Platycosides in roots of may play a crucial role in determining the quality of Goubao pickle through microorganism fermentation. However, biotransfermation of platycosides has not been reviewed during fermentation. In this study, we reviewed platycosides in chemical diversity, metabolic processes , biotransformation of platycosides and pharmacological effects. Finally, we also discussed how to improve the bioactive secondary platycosides we desire by regulating enzymes from microorganisms in the future.

摘要

在中国东北地区,狗宝咸菜是一种以桔梗根为主要原料发酵而成的受欢迎的食品,具有独特的风味和丰富的营养价值。桔梗根中的桔梗皂苷可能通过微生物发酵在决定狗宝咸菜的品质方面发挥关键作用。然而,在发酵过程中桔梗皂苷的生物转化尚未得到综述。在本研究中,我们综述了桔梗皂苷的化学多样性、代谢过程、生物转化及药理作用。最后,我们还讨论了未来如何通过调控微生物中的酶来提高我们所需的生物活性次生桔梗皂苷。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56d9/11283221/02a801e89ad8/gr1.jpg

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