Department of Rheumatism and Immunology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Arch Iran Med. 2024 Jul 1;27(7):400-402. doi: 10.34172/aim.28804.
A patient with longstanding rheumatoid arthritis (RA) complained of spinal cord symptoms after RA relapse. Contrast MRI demonstrated neuromyelitis in the upper thoracic spinal cord, and anti-aquaporin-4 (anti-AQP4) antibody was positive in the serum and cerebrospinal fluid (CSF). Neuromyelitis optica spectrum disorder (NMOSD) was diagnosed after excluding central nervous system (CNS) infection and tumor, and spinal cord symptoms were relieved after high dose of glucocorticoid and immunosuppressant were initiated for treatment.
一位患有长期类风湿性关节炎(RA)的患者在 RA 复发后出现脊髓症状。对比 MRI 显示上胸段脊髓的神经脊髓炎,血清和脑脊液(CSF)中抗水通道蛋白-4(anti-AQP4)抗体阳性。排除中枢神经系统(CNS)感染和肿瘤后,诊断为视神经脊髓炎谱系疾病(NMOSD),并在开始大剂量糖皮质激素和免疫抑制剂治疗后脊髓症状得到缓解。