Postgraduate Program in Dental Sciences, Oral Pathology and Medicine, Department of Dentistry, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
DDS, Oral and Maxillofacial Surgeon, Natal, RN, Brazil.
Head Neck Pathol. 2024 Jul 29;18(1):65. doi: 10.1007/s12105-024-01669-8.
Adenoid ameloblastoma is a newly recognized epithelial odontogenic tumor. Herein, we present the case of a 24-year-old male patient who exhibited swelling in the anterior region and right hemi-mandible. Computed tomography demonstrated the presence of a hypodense osteolytic lesion associated with an impacted tooth. Based on the clinical hypotheses of the dentigerous cyst, odontogenic keratocyst, and ameloblastoma, an incisional biopsy was performed, and the diagnosis of ameloblastoma was rendered. A surgical resection of the tumor was performed. Histopathological examination of the specimen revealed typical areas of ameloblastoma associated with ductiform structures and cell proliferation in a solid storiform pattern, features resembling those found in adenomatoid odontogenic tumor. Based on these findings, the diagnosis of adenoid ameloblastoma was rendered. The accurate diagnosis of this locally infiltrative tumor is essential due to its similarity to other odontogenic neoplasms.
腺样囊腺癌是一种新认识的上皮性牙源性肿瘤。本文报道了 1 例 24 岁男性患者,其表现为前区和右侧下颌骨肿胀。计算机断层扫描显示存在与埋伏牙相关的低密 度溶骨性病变。基于 Dentigerous 囊肿、牙源性角化囊肿和造釉细胞瘤的临床假设,进行了切开活检,诊断为造釉细胞瘤。行肿瘤切除术。标本的组织病理学检查显示典型的造釉细胞瘤区域,伴导管样结构和实性索状的细胞增生,类似于腺样牙源性肿瘤的特征。基于这些发现,诊断为腺样囊腺癌。由于该肿瘤与其他牙源性肿瘤相似,因此准确诊断这种局部浸润性肿瘤至关重要。