氟比洛芬与保泰松治疗急性痛风性关节炎的双盲试验
Double-blind trial of flurbiprofen and phenylbutazone in acute gouty arthritis.
作者信息
Butler R C, Goddard D H, Higgens C S, Hollingworth P, Pease C T, Stodell M A, Scott J T
出版信息
Br J Clin Pharmacol. 1985 Nov;20(5):511-3. doi: 10.1111/j.1365-2125.1985.tb05110.x.
Abstract
Flurbiprofen has been compared with phenylbutazone in a double-blind study involving 33 patients with acute gout. Patients received either flurbiprofen 400 mg daily for 48 h followed by 200 mg daily, or phenylbutazone 800 mg daily for 48 h followed by 400 mg daily. The drugs were of comparable efficacy, while side-effects were uncommon and relatively mild. Flurbiprofen appears to be a satisfactory alternative to phenylbutazone in the management of acute gouty arthritis.
摘要
在一项涉及33例急性痛风患者的双盲研究中，对氟比洛芬和保泰松进行了比较。患者分别接受每日400毫克氟比洛芬治疗48小时，随后每日200毫克；或每日800毫克保泰松治疗48小时，随后每日400毫克。两种药物疗效相当，副作用少见且相对较轻。在急性痛风性关节炎的治疗中，氟比洛芬似乎是保泰松的一种令人满意的替代药物。
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[Double-blind trial: ketoprofen versus phenylbutazone in acute gouty arthritis (author's transl)].双盲试验：酮洛芬与保泰松治疗急性痛风性关节炎的对比研究（作者译）
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