氟比洛芬与保泰松治疗急性痛风性关节炎的双盲试验
Double-blind trial of flurbiprofen and phenylbutazone in acute gouty arthritis.
作者信息
Butler R C, Goddard D H, Higgens C S, Hollingworth P, Pease C T, Stodell M A, Scott J T
出版信息
Br J Clin Pharmacol. 1985 Nov;20(5):511-3. doi: 10.1111/j.1365-2125.1985.tb05110.x.
Abstract
Flurbiprofen has been compared with phenylbutazone in a double-blind study involving 33 patients with acute gout. Patients received either flurbiprofen 400 mg daily for 48 h followed by 200 mg daily, or phenylbutazone 800 mg daily for 48 h followed by 400 mg daily. The drugs were of comparable efficacy, while side-effects were uncommon and relatively mild. Flurbiprofen appears to be a satisfactory alternative to phenylbutazone in the management of acute gouty arthritis.
摘要
在一项涉及33例急性痛风患者的双盲研究中，对氟比洛芬和保泰松进行了比较。患者分别接受每日400毫克氟比洛芬治疗48小时，随后每日200毫克；或每日800毫克保泰松治疗48小时，随后每日400毫克。两种药物疗效相当，副作用少见且相对较轻。在急性痛风性关节炎的治疗中，氟比洛芬似乎是保泰松的一种令人满意的替代药物。
相似文献
1
Double-blind trial of flurbiprofen and phenylbutazone in acute gouty arthritis.氟比洛芬与保泰松治疗急性痛风性关节炎的双盲试验
Br J Clin Pharmacol. 1985 Nov;20(5):511-3. doi: 10.1111/j.1365-2125.1985.tb05110.x.
2
Controlled clinical trial comparing flurbiprofen and phenylbutazone in patients with rheumatoid arthritis.比较氟比洛芬和保泰松治疗类风湿性关节炎患者的对照临床试验。
Curr Med Res Opin. 1977;5(1):74-6. doi: 10.1185/03007997709108980.
3
Treatment of ankylosing spondylitis with flurbiprofen or phenylbutazone.
Eur J Clin Pharmacol. 1977 Apr 20;11(4):263-6. doi: 10.1007/BF00607674.
4
Flurbiprofen in the treatment of ankylosing spondylitis. A comparison with phenylbutazone.
Am J Med. 1986 Mar 24;80(3A):120-6. doi: 10.1016/0002-9343(86)90128-2.
5
Flurbiprofen and phenylbutazone in rheumatoid arthritis and osteoarthrosis: a double-blind study.氟比洛芬与保泰松治疗类风湿性关节炎和骨关节炎：一项双盲研究。
J Assoc Physicians India. 1979 May;27(5):379-83.
6
[Double-blind trial: ketoprofen versus phenylbutazone in acute gouty arthritis (author's transl)].双盲试验：酮洛芬与保泰松治疗急性痛风性关节炎的对比研究（作者译）
Wien Klin Wochenschr. 1976 Sep 3;88(16):535-7.
7
Flurbiprofen in the treatment of acute gout. A comparison with indomethacin.氟比洛芬治疗急性痛风。与吲哚美辛的比较。
Am J Med. 1986 Mar 24;80(3A):134-9. doi: 10.1016/0002-9343(86)90131-2.
8
Double-bind cross-over tiral of flurbiprofen and phenylbutazone in ankylosing spondylitis.氟比洛芬与保泰松治疗强直性脊柱炎的双盲交叉试验
Br Med J. 1974 Nov 30;4(5943):496-9. doi: 10.1136/bmj.4.5943.496.
9
Flurbiprofen versus naproxen in the treatment of rheumatoid arthritis.
Am J Med. 1986 Mar 24;80(3A):105-9. doi: 10.1016/0002-9343(86)90124-5.
10
Double-blind comparison of flurbiprofen and sulindac for the treatment of osteoarthritis.
Am J Med. 1986 Mar 24;80(3A):112-7. doi: 10.1016/0002-9343(86)90126-9.
引用本文的文献
1
Non-steroidal anti-inflammatory drugs for acute gout.非甾体抗炎药治疗急性痛风。
Cochrane Database Syst Rev. 2021 Dec 9;12(12):CD010120. doi: 10.1002/14651858.CD010120.pub3.
2
Efficacy and Safety of Pharmacologic Interventions in Patients Experiencing a Gout Flare: A Systematic Review and Network Meta-Analysis.药物干预对痛风发作患者的疗效和安全性：系统评价和网络荟萃分析。
Arthritis Care Res (Hoboken). 2021 May;73(5):755-764. doi: 10.1002/acr.24402.
3
[Full version of the S2e guidelines on gouty arthritis : Evidence-based guidelines of the German Society of Rheumatology (DGRh)].[痛风性关节炎S2e指南完整版：德国风湿病学会（DGRh）循证指南]
Z Rheumatol. 2016 Aug;75 Suppl 2:11-60. doi: 10.1007/s00393-016-0147-6.
4
Optimizing current treatment of gout.优化痛风的当前治疗。
Nat Rev Rheumatol. 2014 May;10(5):271-83. doi: 10.1038/nrrheum.2014.32. Epub 2014 Mar 11.
5
Multinational evidence-based recommendations for the diagnosis and management of gout: integrating systematic literature review and expert opinion of a broad panel of rheumatologists in the 3e initiative.多国循证推荐意见：痛风的诊断与管理——3e 倡议中广泛的风湿病学家专家组对系统文献回顾和专家意见的整合。
Ann Rheum Dis. 2014 Feb;73(2):328-35. doi: 10.1136/annrheumdis-2013-203325. Epub 2013 Jul 18.
6
Diagnosis and management of gout: a rational approach.痛风的诊断与管理：一种合理的方法。
Postgrad Med J. 2005 Sep;81(959):572-9. doi: 10.1136/pgmj.2004.030692.
7
Gout treatment: what is evidence-based and how do we determine and promote optimized clinical care?痛风治疗：循证依据是什么，我们如何确定并推广优化的临床护理？
Curr Rheumatol Rep. 2005 Jun;7(3):242-9. doi: 10.1007/s11926-996-0046-y.
本文引用的文献
1
208.--INDOMETHACIN IN THE TREATMENT OF ACUTE GOUT.208.——消炎痛治疗急性痛风
Practitioner. 1965 Apr;194:560-5.
2
Gout in the time and person of George IV: a case history.乔治四世时期及人物身上的痛风：一则病史
Ann Rheum Dis. 1962 Dec;21(4):325-38. doi: 10.1136/ard.21.4.325.
3
Introduction to sample size determination and power analysis for clinical trials.临床试验样本量确定与效能分析简介。
Control Clin Trials. 1981 Jun;2(2):93-113. doi: 10.1016/0197-2456(81)90001-5.
4
Double-blind trial of feprazone and phenylbutazone in acute gout.
Curr Med Res Opin. 1980;6(7):445-8. doi: 10.1185/03007998009109465.
5
[Treatment of gout].[痛风的治疗]
Rev Prat. 1983 Oct 1;33(43):2281-94.
6
Treatment of primary gout: the present status.
Arthritis Rheum. 1965 Oct;8(5):911-20. doi: 10.1002/art.1780080502.
7
Comparison of indomethacin and phenylbutazone in acute gout.吲哚美辛与保泰松治疗急性痛风的比较。
Ann Rheum Dis. 1973 Jul;32(4):351-3. doi: 10.1136/ard.32.4.351.
8
Multicentre trial of naproxen and phenylbutazone in acute gout.萘普生和保泰松治疗急性痛风的多中心试验。
Ann Rheum Dis. 1977 Feb;36(1):80-2. doi: 10.1136/ard.36.1.80.
9
[Double-blind trial: ketoprofen versus phenylbutazone in acute gouty arthritis (author's transl)].双盲试验：酮洛芬与保泰松治疗急性痛风性关节炎的对比研究（作者译）
Wien Klin Wochenschr. 1976 Sep 3;88(16):535-7.
10
Double-blind study of fenoprofen versus phenylbutazone in acute gouty arthritis.非诺洛芬与保泰松治疗急性痛风性关节炎的双盲研究。
Arthritis Rheum. 1979 Apr;22(4):425-6. doi: 10.1002/art.1780220420.
Zotero 插件