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萘普生和保泰松治疗急性痛风的多中心试验。

Multicentre trial of naproxen and phenylbutazone in acute gout.

作者信息

Sturge R A, Scott J T, Hamilton E B, Liyanage S P, Dixon A S, Davies J, Engler C

出版信息

Ann Rheum Dis. 1977 Feb;36(1):80-2. doi: 10.1136/ard.36.1.80.

Abstract

Naproxen 750 mg as a single dose followed by 250 mg three times daily has been compared with phenylbutazone 200 mg four times daily for 48 hours followed by 200 mg three times daily for treatment of acute gout in an open study on 41 patients. The drugs were equally effective with few and relatively mild side effects. Naproxen is a useful alternative agent for the treatment of acute gout.

摘要

在一项针对41名患者的开放性研究中,将萘普生单次服用750毫克,随后每日三次、每次250毫克的用药方案,与保泰松每日四次、每次200毫克服用48小时,随后每日三次、每次200毫克的用药方案进行了比较,用于治疗急性痛风。两种药物疗效相当,副作用少且相对较轻。萘普生是治疗急性痛风的一种有用的替代药物。

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