Alshamari Manal, Kourek Christos, Sanoudou Despina, Delis Dimitrios, Dimopoulos Stavros, Rovina Nikoletta, Nanas Serafim, Karatzanos Eleftherios, Philippou Anastassios
Clinical Ergospirometry, Exercise & Rehabilitation Laboratory, 1st Critical Care Medicine Department, Evangelismos Hospital, School of Medicine National and Kapodistrian University of Athens, 10676 Athens, Greece.
Department of Cardiac Rehabilitation, Heart Hospital, Hamad Medical Corporation, 3050 Doha, Qatar.
Rev Cardiovasc Med. 2023 Jan 16;24(1):29. doi: 10.31083/j.rcm2401029. eCollection 2023 Jan.
Aerobic exercise, either continuous or high intensity interval training (HIIT), induces important benefits in chronic heart failure (CHF) patients. Resistance training has been also shown to be beneficial in CHF. However, data regarding combined aerobic exercise and muscle strength training is still limited. The aim of this study was to investigate whether adding strength training to a HIIT protocol within a cardiac rehabilitation (CR) program has a cumulative beneficial effect on the functional capacity (FC) and quality of life (QoL) in patients with CHF.
Forty-four consecutive patients [35 males, ejection fraction (EF) 50%] with CHF under medication enrolled in a 36-session CR program and were randomized in two exercise groups; HIIT (HIIT group) or HIIT combined with strength training (high intensity interval training combined with strength training (COM) group). All patients underwent baseline and endpoint outcome measures of a symptom-limited maximal cardiopulmonary exercise testing (CPET), 1 repetition maximum (1RM) test, muscular endurance test, echocardiography, and Minnesota Living with Heart Failure Questionnaire (MLWHFQ).
Most of the CPET indices, EF, 1RM test, muscular endurance and QoL were improved after the CR program in each exercise training group ( 0.05). However, COM group demonstrated a further improvement in chest muscle testing and workload at anaerobic threshold (AT) compared to HIIT group.
An exercise-based CR program, consisted of either HIIT or HIIT combined with strength training, improves FC and QoL of patients with CHF. However, the addition of strength training to HIIT seems to have further beneficial effects on chest muscle strength and endurance, as well as workload at AT.
The study was registered in ClinicalTrials.gov with number NCT02387411.
有氧运动，无论是持续有氧运动还是高强度间歇训练（HIIT），都能给慢性心力衰竭（CHF）患者带来重要益处。抗阻训练也已被证明对CHF有益。然而，关于有氧运动与肌肉力量训练相结合的数据仍然有限。本研究的目的是调查在心脏康复（CR）计划中，在HIIT方案中加入力量训练是否对CHF患者的功能能力（FC）和生活质量（QoL）有累积益处。
44例连续的CHF患者[35例男性，射血分数（EF）≤50%]正在接受药物治疗，参加了一个为期36节的CR计划，并被随机分为两个运动组；HIIT组（HIIT组）或HIIT联合力量训练组（高强度间歇训练联合力量训练（COM）组）。所有患者均接受了症状限制的最大心肺运动测试（CPET）、1次重复最大值（1RM）测试、肌肉耐力测试、超声心动图和明尼苏达心力衰竭生活问卷（MLWHFQ）的基线和终点结局测量。
在每个运动训练组中，CR计划后，大多数CPET指标、EF、1RM测试、肌肉耐力和QoL均得到改善（P<0.05）。然而，与HIIT组相比，COM组在胸部肌肉测试和无氧阈值（AT）时的工作量方面有进一步改善。
基于运动的CR计划，无论是HIIT还是HIIT联合力量训练，都能改善CHF患者的FC和QoL。然而，在HIIT中加入力量训练似乎对胸部肌肉力量和耐力以及AT时的工作量有进一步的有益影响。
该研究已在ClinicalTrials.gov上注册，注册号为NCT02387411。
