Li Dongdong, Liu Hao, Dai Huimiao, Gao Chuncheng, Yang Pei, Guo Wangang
Department of Cardiology, The Second Affiliated Hospital of Air Force Medical University, 710038 Xi'an, Shaanxi, China.
Rev Cardiovasc Med. 2024 Mar 15;25(3):107. doi: 10.31083/j.rcm2503107. eCollection 2024 Mar.
Side branch (SB) occlusion after main vessel stenting is the main complication in treating coronary bifurcation lesions by provisional stenting. The Jailed Wire Technique (JWT), recommended by the European Bifurcation Club, is a standard technique to deal with this issue. The Jailed Balloon Technique (JBT) has been found to be more effective than the JWT in clinical practice by some interventionists, but it has not been widely accepted. In this meta-analysis, we compared the efficacy and safety of JBT and JWT.
The literature comparing JBT and JWT was systematically reviewed. Stata/MP 17.0 was used to perform a meta-analysis. The primary endpoints were major adverse cardiac events (MACE), cardiac death, myocardial infarction (MI) and target lesion revascularization (TLR). The secondary endpoints were SB occlusion and SB dissection. Aggregated odds ratios and 95% confidence intervals were calculated. A sensitivity analysis was conducted if was 50% or 0.01.
Thirteen studies involving 1789 patients were enrolled. JBT was found to have a significantly lower incidence of MACE, SB occlusion and dissection. The incidence of cardiac death, MI and TLR were also lower in the JBT group, though the differences were not significant.
JBT prevents SB occlusion more effectively and does not increase immediate or long-term complications. JBT, or its modified versions, can be used to treat SBs with a high risk of occlusion.
主血管支架置入术后分支血管(SB)闭塞是临时支架置入治疗冠状动脉分叉病变的主要并发症。欧洲分叉俱乐部推荐的“拘禁导丝技术”(JWT)是处理这一问题的标准技术。一些介入医生发现在临床实践中“拘禁球囊技术”(JBT)比JWT更有效,但尚未被广泛接受。在这项荟萃分析中,我们比较了JBT和JWT的疗效和安全性。
系统回顾比较JBT和JWT的文献。使用Stata/MP 17.0进行荟萃分析。主要终点为主要不良心脏事件(MACE)、心源性死亡、心肌梗死(MI)和靶病变血运重建(TLR)。次要终点为SB闭塞和SB夹层。计算汇总比值比和95%置信区间。如果I²≥50%或P≤0.01,则进行敏感性分析。
纳入13项研究,共1789例患者。发现JBT的MACE、SB闭塞和夹层发生率显著较低。JBT组的心源性死亡、MI和TLR发生率也较低,尽管差异不显著。
JBT能更有效地预防SB闭塞,且不会增加近期或远期并发症。JBT或其改良版本可用于治疗闭塞风险较高的SB。