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一名感染人类免疫缺陷病毒且患有播散性鸟分枝杆菌复合体感染患者的杆菌性血管瘤病

Bacillary Angiomatosis in a Patient With HIV and Disseminated Mycobacterium avium Complex Infection.

作者信息

Caceres Ibeth P, Ruml Angelique, Montejano Rubi, Jalali Omid, Rosen Theodore

机构信息

Dermatology, Baylor College of Medicine, Houston, USA.

Dermatology, Michael E. DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, Houston, USA.

出版信息

Cureus. 2024 Jun 28;16(6):e63392. doi: 10.7759/cureus.63392. eCollection 2024 Jun.

Abstract

is a genus of arthropod-borne bacterial pathogens that typically cause persistent infections of erythrocytes and endothelial cells in mammalian hosts. The species that primarily infect humans are  and  Depending on immune status, the clinical presentation of may differ, manifesting as cat-scratch disease in immunocompetent individuals or bacillary angiomatosis (BA) and peliosis in immunocompromised patients. The cutaneous manifestations of BA are typically characterized by occasionally painful, angiomatous papules and nodules, often with a chronic, persistent course. Herein, we present a case of biopsy-confirmed infection in a 32-year-old HIV-positive female with acquired immunodeficiency syndrome in the setting of disseminated complex infection, an association that has been less frequently described. This case serves as an important reminder to consider uncommon opportunistic infectious etiologies when examining immunocompromised patients, as prompt diagnosis and treatment are essential in this patient population.

摘要

是一类节肢动物传播的细菌病原体,通常会在哺乳动物宿主中引起红细胞和内皮细胞的持续感染。主要感染人类的物种是 和 。根据免疫状态的不同, 的临床表现可能会有所差异,在免疫功能正常的个体中表现为猫抓病,而在免疫功能低下的患者中则表现为杆菌性血管瘤(BA)和紫癜。BA的皮肤表现通常以偶尔疼痛的血管瘤性丘疹和结节为特征,病程往往呈慢性、持续性。在此,我们报告一例经活检确诊的 感染病例,患者为一名32岁的HIV阳性女性,患有获得性免疫缺陷综合征,同时伴有播散性 复合感染,这种关联较少被描述。该病例提醒我们,在检查免疫功能低下的患者时要考虑不常见的机会性感染病因,因为及时诊断和治疗对这类患者至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a227/11283915/638bc0746712/cureus-0016-00000063392-i01.jpg

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