Department of Diabetes and Endocrinology, Mater Dei Hospital, Msida, Malta.
Department of Medicine, Mater Dei Hospital, Msida, Malta.
Br J Hosp Med (Lond). 2024 Jul 30;85(7):1-5. doi: 10.12968/hmed.2024.0086. Epub 2024 Jul 24.
We present a rare case of a 40-year-old nulliparous lady, with no past medical or surgical history, who was diagnosed with metastatic squamous cell carcinoma of the right ovary that originated from a mature cystic ovarian teratoma. Our patient underwent debulking total abdominal hysterectomy, bilateral salpingo-oophorectomy and partial omentectomy followed by postoperative carboplatin and paclitaxel chemotherapy. Rapid disease progression ensued, complicated by severe parathyroid hormone-related protein-induced hypercalcaemia resistant to medical therapy. The patient was treated in a palliative manner and died five months after her diagnosis.
我们报告了一例罕见病例，一名 40 岁的未育妇女，无既往内科或外科病史，被诊断为源自成熟囊性卵巢畸胎瘤的右侧卵巢转移性鳞状细胞癌。患者接受了肿瘤细胞减灭术全子宫切除术、双侧输卵管卵巢切除术和部分网膜切除术，随后进行了卡铂和紫杉醇化疗。疾病迅速进展，并发严重甲状旁腺激素相关蛋白诱导的高钙血症，对药物治疗有抗性。患者接受姑息治疗，在诊断后 5 个月死亡。
