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卵巢来自成熟囊性畸胎瘤的鳞状细胞癌,伴高钙血症。

Squamous cell carcinoma of the ovary arising from a mature cystic teratoma associated with hypercalcaemia.

机构信息

Department of Diabetes and Endocrinology, Mater Dei Hospital, Msida, Malta.

Department of Medicine, Mater Dei Hospital, Msida, Malta.

出版信息

Br J Hosp Med (Lond). 2024 Jul 30;85(7):1-5. doi: 10.12968/hmed.2024.0086. Epub 2024 Jul 24.

Abstract

We present a rare case of a 40-year-old nulliparous lady, with no past medical or surgical history, who was diagnosed with metastatic squamous cell carcinoma of the right ovary that originated from a mature cystic ovarian teratoma. Our patient underwent debulking total abdominal hysterectomy, bilateral salpingo-oophorectomy and partial omentectomy followed by postoperative carboplatin and paclitaxel chemotherapy. Rapid disease progression ensued, complicated by severe parathyroid hormone-related protein-induced hypercalcaemia resistant to medical therapy. The patient was treated in a palliative manner and died five months after her diagnosis.

摘要

我们报告了一例罕见病例,一名 40 岁的未育妇女,无既往内科或外科病史,被诊断为源自成熟囊性卵巢畸胎瘤的右侧卵巢转移性鳞状细胞癌。患者接受了肿瘤细胞减灭术全子宫切除术、双侧输卵管卵巢切除术和部分网膜切除术,随后进行了卡铂和紫杉醇化疗。疾病迅速进展,并发严重甲状旁腺激素相关蛋白诱导的高钙血症,对药物治疗有抗性。患者接受姑息治疗,在诊断后 5 个月死亡。

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