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了解电子烟对心血管系统的影响:文献综述

Understanding the Cardiovascular Fallout of E-cigarettes: A Comprehensive Review of the Literature.

作者信息

Chaturvedi Devansh, Attia Hussein Mahmoud Hussein, Isaac Ashley, Atla Ragha Harshitha, Shakeel Juveria N, Heredia Maria, Marepalli Nitheesha Reddy, Shukla Pranav S, Gardezi Maira, Zeeshan Madiha, Ashraf Tehreem

机构信息

Medicine, Dr Chaturvedi Cancer Hospital and Research Institute, Gorakhpur, IND.

Internal Medicine, King George's Medical University, Lucknow, IND.

出版信息

Cureus. 2024 Jun 29;16(6):e63489. doi: 10.7759/cureus.63489. eCollection 2024 Jun.

DOI:10.7759/cureus.63489
PMID:39081430
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11287103/
Abstract

E-cigarettes (ECs) deliver chemicals, including nicotine. They can cause respiratory distress, addiction, cardiovascular effects, and death. More research is needed, especially regarding their impact on the cardiovascular system (CVS) and during pregnancy. Our article aims to fill this gap by summarizing studies elaborating upon the current impact of ECs and the components thereof on the CVS. Acute respiratory distress outbreaks, nicotine addiction, CVS effects, and deaths have been occasionally reported within this cohort, although these events are not uncommon with neighboring age groups. Randomized control trials implying ECs have some contribution toward quitting smoking have been studied. To regulate EC distribution, the Food and Drug Administration (FDA) and Centers for Disease Control and Prevention (CDC) have created key checkpoints. Additionally, taxation, pricing, age restriction, and media campaigns could be modulated to significantly reduce illicit sales. Education to the users, distributors, and regulators about this product can also play an aiding role in promoting responsible EC use. Another strategy about licensing could be employed, which could incentivize genuine resellers. The effects on CVS and child-bearing by ECs are grim, which calls for strict regulation, awareness, and avoidance by the teetotaler public. They may help individuals stop smoking but not without harming themselves. Strict regulations are necessary to prevent non-judicious use of these devices.

摘要

电子烟会释放包括尼古丁在内的化学物质。它们会导致呼吸窘迫、成瘾、心血管问题以及死亡。还需要更多研究,尤其是关于它们对心血管系统(CVS)以及孕期的影响。我们的文章旨在通过总结阐述电子烟及其成分对心血管系统当前影响的研究来填补这一空白。在这个群体中偶尔会报告急性呼吸窘迫爆发、尼古丁成瘾、心血管系统影响和死亡情况,不过这些事件在相邻年龄组中也并不罕见。已经对暗示电子烟对戒烟有一定作用的随机对照试验进行了研究。为了规范电子烟的销售,美国食品药品监督管理局(FDA)和疾病控制与预防中心(CDC)设立了关键检查点。此外,可以调整税收、定价、年龄限制和媒体宣传活动,以大幅减少非法销售。对电子烟使用者、经销商和监管者进行关于该产品的教育,也有助于促进对电子烟的合理使用。还可以采用另一种许可策略,这可以激励正规经销商。电子烟对心血管系统和生育的影响很严重,这就要求完全不使用电子烟的公众进行严格监管、提高认识并加以避免。电子烟可能有助于个人戒烟,但并非没有危害。必须制定严格的规定以防止对这些产品的不当使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c1/11287103/5c27a2531c96/cureus-0016-00000063489-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c1/11287103/f58607f97733/cureus-0016-00000063489-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c1/11287103/59ded4592be9/cureus-0016-00000063489-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c1/11287103/5c27a2531c96/cureus-0016-00000063489-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c1/11287103/f58607f97733/cureus-0016-00000063489-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c1/11287103/59ded4592be9/cureus-0016-00000063489-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c1/11287103/5c27a2531c96/cureus-0016-00000063489-i03.jpg

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本文引用的文献

1
Population-Based Disease Odds for E-Cigarettes and Dual Use versus Cigarettes.基于人群的电子烟与卷烟双重使用疾病比值。
NEJM Evid. 2024 Mar;3(3):EVIDoa2300229. doi: 10.1056/EVIDoa2300229. Epub 2024 Feb 27.
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Electronic cigarettes and cardiovascular disease: epidemiological and biological links.电子烟与心血管疾病:流行病学和生物学关联。
Pflugers Arch. 2024 Jun;476(6):875-888. doi: 10.1007/s00424-024-02925-0. Epub 2024 Feb 20.
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Association between electronic nicotine delivery systems use and risk of stroke: a meta-analysis of 1,024,401 participants.
电子尼古丁传送系统使用与中风风险之间的关联:对1,024,401名参与者的荟萃分析
Arch Med Sci. 2023 Aug 27;19(5):1538-1540. doi: 10.5114/aoms/171473. eCollection 2023.
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Don't Go Vaping My Heart: A Case of Vaping-Associated Cardiomyopathy and Lung Injury.别“蒸”伤我的心:一例与电子烟相关的心肌病和肺损伤病例
Cureus. 2023 Jul 31;15(7):e42723. doi: 10.7759/cureus.42723. eCollection 2023 Jul.
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Evaluation of the Effects of e-Cigarette Aerosol Extracts and Tobacco Cigarette Smoke Extracts on RAW264.7 Cells.电子烟气溶胶提取物和香烟烟雾提取物对RAW264.7细胞影响的评估。
ACS Omega. 2023 Aug 1;8(32):29336-29345. doi: 10.1021/acsomega.3c02758. eCollection 2023 Aug 15.
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Trends in Electronic Cigarette Use Among US Adults With a History of Cardiovascular Disease.有心血管疾病史的美国成年人使用电子烟的趋势。
JAMA Netw Open. 2023 Aug 1;6(8):e2328962. doi: 10.1001/jamanetworkopen.2023.28962.
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Electronic Cigarette Vaping with Nicotine Causes Increased Thrombogenicity and Impaired Microvascular Function in Healthy Volunteers: A Randomised Clinical Trial.电子烟尼古丁吸入增加健康志愿者的血栓形成性和损害微血管功能:一项随机临床试验。
Cardiovasc Toxicol. 2023 Aug;23(7-8):255-264. doi: 10.1007/s12012-023-09802-9. Epub 2023 Aug 7.
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The toxic effects of electronic cigarette aerosol and cigarette smoke on cardiovascular, gastrointestinal and renal systems in mice.电子烟气溶胶和香烟烟雾对小鼠心血管、胃肠道和肾脏系统的毒性作用。
Sci Rep. 2023 Jul 31;13(1):12366. doi: 10.1038/s41598-023-39201-7.
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Nutrients. 2023 Jul 14;15(14):3140. doi: 10.3390/nu15143140.
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