Department of Pharmacology, School of Pharmaceutical Sciences, RIMT University, Mandi Gobindgarh, Punjab, 147301, India.
Amity Institute of Pharmacy, Amity University Rajasthan, Jaipur, 303002, India.
Antiinflamm Antiallergy Agents Med Chem. 2024;23(4):215-229. doi: 10.2174/0118715230320581240711063558.
It is possible for psoriasis to manifest at any point in a person's life, regardless of their age, gender, or geographic location. It is a chronic immune-linked inflammatory skin illness that affects individuals of various racial and ethnic origins. It is recognized to be a longlasting condition. Because of the significant contribution that natural products have made, there has been a significant advancement in the treatment of skin illnesses such as psoriasis. The biggest number of phytochemicals derived from a wide range of plants and herbs are now being used in a variety of applications throughout the whole world. Additionally, a number of phytochemicals, including aloe-emodin, psoralen, curcumin, and others, have been effectively extracted in pure or clear form, and they have shown a great deal of efficacy in the treatment of psoriasis illness. There is evidence that few herbal remedies are effective, and the occurrence of these phytochemicals provides more proof. When synthetic medications are used for chronic therapy, they may cause a variety of adverse consequences; hence, the exploration of natural pharmaceuticals can give a successful natural treatment with a minimal amount of adverse effects. Within the scope of this concise review, a number of plant sources that possess anti-psoriatic activity are investigated, and the antipsoriatic effects of these plant sources are shown on a number of animal models using particular pathways.
银屑病可以在任何人的一生中的任何时候出现，无论其年龄、性别或地理位置如何。它是一种慢性免疫相关的炎症性皮肤疾病，影响着不同种族和民族的个体。它被认为是一种持久的疾病。由于天然产物做出了重大贡献，在治疗银屑病等皮肤疾病方面取得了重大进展。现在，从各种各样的植物和草药中提取的最大数量的植物化学物质正在全球范围内的各种应用中使用。此外，许多植物化学物质，包括大黄素、补骨脂素、姜黄素等，已经被有效地提取出来，并且以纯品或透明品的形式存在，它们在治疗银屑病方面显示出了很大的疗效。有证据表明，一些草药疗法是有效的，而这些植物化学物质的出现提供了更多的证据。当使用合成药物进行慢性治疗时，它们可能会引起多种不良反应；因此，对天然药物的探索可以提供一种成功的、副作用最小的自然疗法。在这篇简短的综述中，研究了一些具有抗银屑病活性的植物来源，并展示了这些植物来源通过特定途径在一些动物模型上的抗银屑病作用。
