Dabholkar Neha, Rapalli Vamshi K, Singhvi Gautam
Industrial Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani, India.
Phytother Res. 2021 May;35(5):2429-2444. doi: 10.1002/ptr.6973. Epub 2020 Dec 5.
Psoriasis is a multifactorial and chronic skin disorder. It is a recurrent disease that requires incessant therapy. Psoriasis treatment includes topical and systemic routes using synthetic drugs that lead to severe unwanted adverse effects. Herbal therapy is widely used for thousands of years in countries like China and India. The use of herbal therapy in the developed region enhanced to a great extent and showed better efficacy towards psoriasis alone or as adjuvant to synthetic therapy. Herbal medicines have gained great attention in the treatment of psoriasis due to their lesser side effects compared to synthetic drugs. In this review, the various plant sources which have been found effective in psoriasis and can be used to develop novel therapeutics have been discussed. The mechanisms by which the phytoconstituents elicit anti-psoriatic activity and various research studies that have proven the effectiveness of these natural products have also been compiled in this review.
银屑病是一种多因素的慢性皮肤疾病。它是一种复发性疾病，需要持续治疗。银屑病的治疗包括使用合成药物的局部和全身途径，但这些药物会导致严重的不良副作用。草药疗法在中国和印度等国家已经被广泛使用了数千年。在发达地区，草药疗法的使用也有了很大程度的增加，并且单独使用或作为合成疗法的辅助手段对银屑病显示出更好的疗效。与合成药物相比，草药由于副作用较小，在银屑病治疗中受到了极大关注。在这篇综述中，讨论了已发现对银屑病有效的各种植物来源，这些植物可用于开发新型疗法。本综述还汇编了植物成分发挥抗银屑病活性的机制以及各种证明这些天然产物有效性的研究。
