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1990 年至 2019 年巴西及其联邦单位肺癌负担和归因于职业风险因素的死亡率。

The burden of lung cancer and mortality attributable to occupational risk factors between 1990 and 2019 in Brazil and federative units.

机构信息

Universidade Federal de Juiz de Fora, Programa de Pós-Graduação em Saúde Coletiva, Juiz de Fora, MG, Brazil.

Universidade Federal de Minas Gerais, Departamento de Enfermagem Materno-Infantil e Saúde Pública, Belo Horizonte, MG, Brazil.

出版信息

Public Health. 2024 Oct;235:94-101. doi: 10.1016/j.puhe.2024.06.035. Epub 2024 Jul 30.

Abstract

OBJECTIVE

The aim of this study was to analyse the attributable risk of mortality and DALYs (Disability Adjusted Life Years) due to occupational carcinogens for lung cancer between 1990 and 2019 in Brazil and federation units, as well as its relationship with the Socio-demographic Index (SDI).

STUDY DESIGN

Epidemiological study.

METHODS

This is an epidemiological study that used GBD 2019 (Global Burden of Disease Study) estimates of lung cancer mortality rates and DALYs attributable to occupational carcinogens. The relationship between these rates and SDI was assessed using panel data analysis.

RESULTS

In Brazil, occupational exposure to asbestos, silica and diesel vapours accounted for more than 85.00% of lung cancer deaths and DALYs attributable to occupational carcinogens in both sexes between 1990 and 2019. An increase in both rates was observed in women for almost all the occupational carcinogens assessed, especially in the North and Northeast regions of the country, with diesel vapours standing out the most.

CONCLUSIONS

The present study highlighted the urge to characterise exposure to occupational risks for lung cancer, especially for the female population in the North and Northeast regions of Brazil.

摘要

目的

本研究旨在分析 1990 年至 2019 年巴西和联邦单位因职业致癌物导致的肺癌死亡率和伤残调整生命年(DALYs)的归因风险,以及其与社会人口指数(SDI)的关系。

研究设计

流行病学研究。

方法

这是一项使用 GBD 2019(全球疾病负担研究)估计的肺癌死亡率和归因于职业致癌物的 DALYs 的流行病学研究。使用面板数据分析评估这些比率与 SDI 之间的关系。

结果

在巴西,1990 年至 2019 年,男女两性因职业接触石棉、二氧化硅和柴油蒸气导致的肺癌死亡和归因于职业致癌物的 DALYs 超过 85.00%。几乎所有评估的职业致癌物的这两个比率在女性中均呈上升趋势,尤其是在该国的北部和东北部地区,柴油蒸气最为突出。

结论

本研究强调了对巴西北部和东北部地区女性人群的肺癌职业风险暴露进行特征描述的紧迫性。

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