Department of Oncology, Ningbo Municipal Hospital of Traditional Chinese Medicine (TCM), Affiliated Hospital of Zhejiang Chinese Medical University, Ningbo, Zhejiang, China.
Department of Spleen and Stomach, Shanghai Pudong New Area Traditional Chinese Medicine Hospital, Shanghai, China.
J Occup Health. 2024 Jan 4;66(1). doi: 10.1093/joccuh/uiae040.
Based on data from the Global Burden of Disease study, the burden of cancer attributable to occupational risks between 1990 and 2019 was explored.
The estimated burden in different regions was compared in terms of the age-standardized death rates (ASDRs), age-standardized disability-adjusted life years (DALYs) rates, and corresponding estimated annual percentage changes (EAPCs). The comparative risk assessment framework was used to estimate the risk of death and DALYs attributable to occupational risk factors.
Globally from 1990 to 2019, ASDRs decreased (EAPC = -0.69; 95% CI: -0.76 to -0.61), and age-standardized DALY rates decreased (EAPC = -0.99; 95% CI: -1.05 to -0.94). In terms of the global age distribution of cancer attributable to occupational risk factors, the death rate and DALY rates increased with age. In addition, from 1990 to 2019, the number of deaths, DALYs, ASDRs, and age-standardized DALY rates in men were higher than those in women, and the cancer burden grew fastest in Georgia (EAPC = 5.04), Croatia (EAPC = 4.01), and Honduras (EAPC = 3.54). Moreover, as the sociodemographic index (SDI) value of a country or region increased, its burden of cancer attributable to occupational risk factors rapidly increased.
The global cancer burden attributable to occupational risk factors declined from 1990 to 2019, was higher in men than in women, and was concentrated in middle-aged and older adults. The baseline cancer burdens of regions or countries increased as their SDI values increased and were especially high in high-SDI regions or countries.
基于全球疾病负担研究的数据，探讨了 1990 年至 2019 年与职业风险相关的癌症负担。
比较了不同地区的年龄标准化死亡率（ASDR）、年龄标准化伤残调整生命年（DALY）率以及相应的估计年变化百分比（EAPC）的差异。采用比较风险评估框架来估计与职业风险因素相关的死亡和 DALY 的风险。
全球范围内，1990 年至 2019 年 ASDR 呈下降趋势（EAPC=-0.69；95%CI：-0.76 至-0.61），年龄标准化 DALY 率呈下降趋势（EAPC=-0.99；95%CI：-1.05 至-0.94）。就归因于职业风险因素的癌症在全球年龄分布而言，死亡率和 DALY 率随年龄增长而增加。此外，1990 年至 2019 年，男性的死亡人数、DALY、ASDR 和年龄标准化 DALY 率均高于女性，癌症负担增长最快的国家或地区为格鲁吉亚（EAPC=5.04）、克罗地亚（EAPC=4.01）和洪都拉斯（EAPC=3.54）。此外，随着一个国家或地区社会人口指数（SDI）值的增加，其归因于职业风险因素的癌症负担迅速增加。
1990 年至 2019 年，与职业风险相关的全球癌症负担呈下降趋势，男性高于女性，且集中在中年及以上人群。地区或国家的癌症基线负担随 SDI 值的增加而增加，在高 SDI 地区或国家尤为突出。
