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伴有淀粉样血管病的亚急性海绵状脑病（克雅氏病）

Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease) with amyloid angiopathy.

作者信息

Keohane C, Peatfield R, Duchen L W

出版信息

J Neurol Neurosurg Psychiatry. 1985 Nov;48(11):1175-8. doi: 10.1136/jnnp.48.11.1175.

DOI:10.1136/jnnp.48.11.1175
PMID:3908618
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1028581/
Abstract

A case is reported of Creutzfeldt-Jakob disease associated with amyloid infiltration of cerebral vessels. The duration of progressive dementia was only 4 months. Neuritic plaques were not a feature of the pathology. This report emphasises the association of spongiform encephalopathy with the presence of amyloid in the brain.

摘要

报告了一例与脑血管淀粉样蛋白浸润相关的克雅氏病。进行性痴呆的病程仅4个月。神经炎性斑块并非病理学特征。本报告强调了海绵状脑病与大脑中淀粉样蛋白存在之间的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7807/1028581/b692fa83c0cf/jnnpsyc00115-0106-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7807/1028581/b692fa83c0cf/jnnpsyc00115-0106-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7807/1028581/b692fa83c0cf/jnnpsyc00115-0106-a.jpg

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本文引用的文献

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Congophilic angiopathy of the brain: a clinical and pathological report on two siblings.脑嗜刚果红血管病：两例同胞患者的临床与病理报告
J Neurol Neurosurg Psychiatry. 1982 May;45(5):396-408. doi: 10.1136/jnnp.45.5.396.
2
Familial cerebellar ataxia with cerebrovascular amyloid.伴有脑血管淀粉样变的家族性小脑共济失调
J Neurol Neurosurg Psychiatry. 1982 Mar;45(3):271-3. doi: 10.1136/jnnp.45.3.271.
3
Familial cerebral amyloidosis and spongiform encephalopathy.家族性脑淀粉样变性和海绵状脑病。
伴有淀粉样血管病的克雅氏病：通过免疫学分析和传播实验进行诊断
Acta Neuropathol. 1992;83(5):559-63. doi: 10.1007/BF00310037.
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Current status review: cerebral amyloid.现状综述：脑淀粉样蛋白
Int J Exp Pathol. 1992 Aug;73(4):535-50.
J Neurol Neurosurg Psychiatry. 1982 Jan;45(1):37-45. doi: 10.1136/jnnp.45.1.37.
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The familial occurrence of Creutzfeldt-Jakob disease and Alzheimer's disease.克雅氏病和阿尔茨海默病的家族性发病情况。
Brain. 1981 Sep;104(3):535-58. doi: 10.1093/brain/104.3.535.
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Creutzfeldt-Jakob disease virus isolations from the Gerstmann-Sträussler syndrome with an analysis of the various forms of amyloid plaque deposition in the virus-induced spongiform encephalopathies.从格斯特曼-施特劳斯勒综合征中分离出克雅氏病病毒，并对病毒诱导的海绵状脑病中各种形式的淀粉样斑块沉积进行分析。
Brain. 1981 Sep;104(3):559-88. doi: 10.1093/brain/104.3.559.
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Hereditary cerebral haemorrhage with amyloidosis.遗传性脑出血伴淀粉样变性
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7
[Association of Alzheimer's disease and Creutzfeldt-Jakob's disease (author's transl)].阿尔茨海默病与克雅氏病的关联（作者译）
Acta Neurol Belg. 1977 Jul-Aug;77(4):202-12.
8
The incidence of cerebral amyloid angiopathy in Alzheimer's disease.阿尔茨海默病中脑淀粉样血管病的发病率。
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