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Maternal prolactin or estrogen signaling in hepatocytes does not regulate iron homeostasis during pregnancy.

作者信息

Zhang Vida, Fisher Allison L, Hewitt Marguerite S, Ganz Tomas, Nemeth Elizabeta, Sangkhae Veena

机构信息

UCLA Center for Iron Disorders, UCLA Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, David Geffen School of Medicine, Los Angeles, California.

Nephrology Division and Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

出版信息

Haematologica. 2024 Dec 1;109(12):4116-4119. doi: 10.3324/haematol.2024.285456.

DOI:10.3324/haematol.2024.285456
PMID:39086305
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11609807/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dce1/11609807/60556ed9cb9b/1094116.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dce1/11609807/d5a840d5f9e0/1094116.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dce1/11609807/60556ed9cb9b/1094116.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dce1/11609807/d5a840d5f9e0/1094116.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dce1/11609807/60556ed9cb9b/1094116.fig2.jpg

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本文引用的文献

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Iron Homeostasis During Pregnancy: Maternal, Placental, and Fetal Regulatory Mechanisms.妊娠期间的铁稳态：母体、胎盘和胎儿的调节机制。
Annu Rev Nutr. 2023 Aug 21;43:279-300. doi: 10.1146/annurev-nutr-061021-030404. Epub 2023 May 30.
2
INTERGROWTH-21 Identifies High Prevalence of Low Symphysis-Fundal Height in Indigenous Pregnant Women Experiencing Multiple Infections, Nutrient Deficiencies, and Inflammation: The Maternal Infections, Nutrient Deficiencies, and Inflammation (MINDI) Cohort.INTERGROWTH-21研究发现，在患有多种感染、营养缺乏和炎症的原住民孕妇中，耻上宫高偏低的情况很普遍：母婴感染、营养缺乏和炎症（MINDI）队列研究。
Curr Dev Nutr. 2021 Apr 12;5(4):nzab012. doi: 10.1093/cdn/nzab012. eCollection 2021 Apr.
3
Hormone concentrations throughout uncomplicated pregnancies: a longitudinal study.
正常孕期激素浓度的纵向研究
BMC Pregnancy Childbirth. 2016 Jul 4;16(1):146. doi: 10.1186/s12884-016-0937-5.
4
Circulating Hepcidin-25 Is Reduced by Endogenous Estrogen in Humans.内源性雌激素可降低人体循环中的铁调素-25水平。
PLoS One. 2016 Feb 11;11(2):e0148802. doi: 10.1371/journal.pone.0148802. eCollection 2016.
5
Hepcidin levels in hyperprolactinemic women monitored by nanopore thin film based assay: correlation with pregnancy-associated hormone prolactin.
Nanomedicine. 2015 May;11(4):871-8. doi: 10.1016/j.nano.2015.01.008. Epub 2015 Feb 4.
6
Identification of estrogen-responsive genes based on the DNA binding properties of estrogen receptors using high-throughput sequencing technology.利用高通量测序技术基于雌激素受体的DNA结合特性鉴定雌激素反应基因。
Acta Pharmacol Sin. 2015 Jan;36(1):24-31. doi: 10.1038/aps.2014.123. Epub 2014 Dec 15.
7
Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential.雌激素受体α（ERα）和β（ERβ）：亚型选择性配体及临床潜力。
Steroids. 2014 Nov;90:13-29. doi: 10.1016/j.steroids.2014.06.012. Epub 2014 Jun 24.
8
The small molecule, genistein, increases hepcidin expression in human hepatocytes.小分子染料木黄酮可增加人肝细胞中血红素的表达。
Hepatology. 2013 Oct;58(4):1315-25. doi: 10.1002/hep.26490. Epub 2013 Aug 19.
9
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