Li XiaoLan, Li Min, Tian Juan, Shi Zi-Wei, Wang Ling-Zhi, Song Kui
Department of Hematology, The First Affiliated Hospital of Jishou University, Jishou, Hunan, People's Republic of China.
Department of Pharmacy, The First Affiliated Hospital of Jishou University, Jishou, Hunan, People's Republic of China.
J Blood Med. 2024 Jul 29;15:325-330. doi: 10.2147/JBM.S465827. eCollection 2024.
Multiple myeloma (MM) is a malignancy of plasma cells that can cause anemia due to renal failure and bone marrow failure. Secondary polycythemia (SE) is a clinically rare disease that involves the overproduction of red blood cells. To our knowledge, the association of multiple myeloma and polycythemia has been reported, but the association of SE and multiple myeloma is rare and has been infrequently reported in literature. In contrast to anemia, the presence of polycythemia in multiple myeloma patients is a rare finding. A patient of IgA-λ multiple myeloma with secondary erythrocytosis recently admitted to our department is now reported as follows and relevant literature is reviewed to improve clinicians' awareness of such rare comorbidities.
多发性骨髓瘤（MM）是一种浆细胞恶性肿瘤，可因肾衰竭和骨髓衰竭导致贫血。继发性红细胞增多症（SE）是一种临床罕见疾病，涉及红细胞过度生成。据我们所知，多发性骨髓瘤与红细胞增多症的关联已有报道，但SE与多发性骨髓瘤的关联罕见，且文献中鲜有报道。与贫血相反，多发性骨髓瘤患者中出现红细胞增多症是一个罕见的发现。现将我院近期收治的1例IgA-λ型多发性骨髓瘤伴继发性红细胞增多症患者报告如下，并复习相关文献，以提高临床医生对这种罕见合并症的认识。
