Quigley Mindy, McKenna Charly, Webb Tracy L
Veterinary Clinical Research Office, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, United States.
Clinical Studies, Department of Clinical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Front Vet Sci. 2024 Jul 17;11:1418747. doi: 10.3389/fvets.2024.1418747. eCollection 2024.
A successful clinical trial requires participants, but many factors can impede effective study recruitment. To better recruit for quality veterinary clinical trials in client-owned animals that lead to improved evidence-based patient care and outcomes, there is a collective need to share and implement current best practices for recruitment strategies. These strategies should utilize a holistic view of recruitment, encompassing study design and logistics, representative participation, incentives, personnel resources, advertising, and participant retention. Although human clinical trial data and resources can provide guidance, effort also needs to be put into evaluating current practices and opportunities for process improvement that are specific to the conduct of veterinary clinical trials. Considering the power of pets as naturally occurring models of disease and as sentinels, improved conduct of veterinary clinical research has the potential to inform human health outcomes. Continued development of collaborations surrounding best practices and training opportunities in veterinary clinical research will improve the impact of veterinary clinical trials teams, while also promoting workforce development and alternate career paths for veterinary professionals.
一项成功的临床试验需要参与者,但许多因素会阻碍有效的研究招募。为了更好地招募客户拥有的动物参与高质量的兽医临床试验,从而改善基于证据的患者护理和治疗结果,大家共同需要分享并实施当前招募策略的最佳实践。这些策略应采用整体的招募视角,涵盖研究设计与后勤、代表性参与、激励措施、人力资源、广告宣传以及参与者留存。尽管人类临床试验数据和资源可提供指导,但也需要努力评估当前的实践以及兽医临床试验实施过程中具体的改进机会。考虑到宠物作为自然发生的疾病模型和哨兵的作用,改进兽医临床研究的开展有潜力为人类健康结果提供信息。围绕兽医临床研究最佳实践和培训机会持续开展合作,将提高兽医临床试验团队的影响力,同时也促进兽医专业人员的劳动力发展和其他职业道路。