de Souza Araújo Larissa, Santana Larice Aparecida Rezende, Otenio Marcelo Henrique, Nascimento Clerison Wagner, Cerqueira Ana Flávia Lawall Werneck, Rodarte Mirian Pereira
Faculty of Pharmacy, Department of Pharmaceutical Sciences, Federal University of Juiz de Fora, Rua José Lourenço Kelmer, S/N-São Pedro, Juiz de Fora, Minas Gerais State, 36036-900, Brazil.
Embrapa Dairy Cattle, Research Center, Juiz de Fora, Av. Eugênio Do Nascimento, 610-Aeroporto, Juiz de Fora, Minas Gerais State, 36038-330, Brazil.
Appl Biochem Biotechnol. 2024 Dec;196(12):9049-9063. doi: 10.1007/s12010-024-05036-9. Epub 2024 Aug 1.
It is of fundamental interest to research and develop innovative biotechnologies, as well as bioproducts that replace or are alternatives to those of non-renewable origin, such as biosurfactants in relation to traditional surfactants used in various sectors. Consequently, there are a large number of experimental studies addressing different subjects, especially with the use of bacteria of the genus Pseudomonas; however, there is a lack of work that demonstrates the evaluation of this science produced to date. Therefore, this article discusses the production of biosurfactants by Pseudomonas with the aim of surveying and analyzing experimental articles on this topic. To realize this, a systematic search was carried out with well-defined temporal space, databases, and inclusion and exclusion criteria, based on metric studies that guided what information would be collected and the method of evaluation. Therefore, a large number of articles were selected, which demonstrated Pseudomonas aeruginosa as the bioagent mostly used in the tests, which aimed to improve the process in the area. Furthermore, interest in this field has increased over the years, predominantly in emerging market countries, where the most prominent authors on the topic are found. Therefore, it is necessary that there is an expansion of interest in the area to make the production of biosurfactants cheaper in areas that currently have greater development deficiencies, such as means of purifying the bioprocess and reducing foam formation in the bioprocess.
研究和开发创新生物技术以及可替代不可再生来源产品的生物制品具有根本重要性,例如与各领域使用的传统表面活性剂相关的生物表面活性剂。因此,有大量针对不同主题的实验研究,特别是使用假单胞菌属细菌进行的研究;然而,缺乏对迄今为止所产生的这一科学成果进行评估的工作。所以,本文讨论假单胞菌产生生物表面活性剂的情况,目的是调查和分析关于该主题的实验文章。为实现这一点,基于指导收集何种信息及评估方法的计量研究,在明确界定的时间范围、数据库以及纳入和排除标准的基础上进行了系统搜索。因此,挑选出了大量文章,这些文章表明铜绿假单胞菌是测试中最常用的生物制剂,旨在改进该领域的工艺。此外,多年来对该领域的兴趣有所增加,主要是在新兴市场国家,这些国家有该主题最杰出的作者。因此,有必要扩大对该领域的兴趣,以便在目前发展不足较多的领域降低生物表面活性剂的生产成本,比如生物过程的纯化方法以及减少生物过程中的泡沫形成。