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本文引用的文献

1
Real-world trough concentrations and effectiveness of long-acting cabotegravir and rilpivirine: a multicenter prospective observational study in Switzerland.长效卡博特韦和rilpivirine的真实世界谷浓度及有效性:瑞士的一项多中心前瞻性观察研究
Lancet Reg Health Eur. 2023 Dec 13;36:100793. doi: 10.1016/j.lanepe.2023.100793. eCollection 2024 Jan.
2
Development, validation and clinical implementation of a UPLC-MS/MS bioanalytical method for simultaneous quantification of cabotegravir and rilpivirine E-isomer in human plasma.建立、验证并临床应用 UPLC-MS/MS 法,用于人血浆中卡替拉韦和利匹韦林 E-对映异构体的同时定量分析。
J Pharm Biomed Anal. 2024 Jan 20;238:115832. doi: 10.1016/j.jpba.2023.115832. Epub 2023 Nov 4.
3
Expanded Multivariable Models to Assist Patient Selection for Long-Acting Cabotegravir + Rilpivirine Treatment: Clinical Utility of a Combination of Patient, Drug Concentration, and Viral Factors Associated With Virologic Failure.扩展多变量模型以辅助长效卡替拉韦+利匹韦林治疗的患者选择:与病毒学失败相关的患者、药物浓度和病毒因素组合的临床效用。
Clin Infect Dis. 2023 Nov 17;77(10):1423-1431. doi: 10.1093/cid/ciad370.
4
Long-Acting Cabotegravir and Rilpivirine Dosed Every 2 Months in Adults With Human Immunodeficiency Virus 1 Type 1 Infection: 152-Week Results From ATLAS-2M, a Randomized, Open-Label, Phase 3b, Noninferiority Study.长效卡替拉韦和利匹韦林每 2 个月给药 1 次治疗人类免疫缺陷病毒 1 型感染成人患者:ATLAS-2M 研究 152 周结果,这是一项随机、开放标签、3b 期、非劣效性研究。
Clin Infect Dis. 2023 May 3;76(9):1646-1654. doi: 10.1093/cid/ciad020.
5
Real-Life Therapeutic Concentration Monitoring of Long-Acting Cabotegravir and Rilpivirine: Preliminary Results of an Ongoing Prospective Observational Study in Switzerland.长效卡博特韦和rilpivirine的实际治疗浓度监测:瑞士一项正在进行的前瞻性观察研究的初步结果。
Pharmaceutics. 2022 Jul 29;14(8):1588. doi: 10.3390/pharmaceutics14081588.
6
Regulation of drug-metabolizing enzymes by sex-related hormones: clinical implications for transgender medicine.性相关激素对药物代谢酶的调节: transgender medicine 的临床意义。
Trends Pharmacol Sci. 2022 Jul;43(7):582-592. doi: 10.1016/j.tips.2022.03.006. Epub 2022 Apr 26.
7
Sex and Gender Differences in Clinical Pharmacology: Implications for Transgender Medicine.临床药理学中的性别差异:对跨性别医学的影响。
Clin Pharmacol Ther. 2021 Oct;110(4):897-908. doi: 10.1002/cpt.2234. Epub 2021 May 2.
8
Exploring predictors of HIV-1 virologic failure to long-acting cabotegravir and rilpivirine: a multivariable analysis.探索长效卡替拉韦和利匹韦林治疗 HIV-1 病毒学失败的预测因素:多变量分析。
AIDS. 2021 Jul 15;35(9):1333-1342. doi: 10.1097/QAD.0000000000002883.
9
Propranolol metabolism in normal subjects: association with sex steroid hormones.正常受试者体内普萘洛尔的代谢:与性类固醇激素的关联。
Clin Pharmacol Ther. 1994 Aug;56(2):127-32. doi: 10.1038/clpt.1994.115.

Concomitant use of anabolic androgen steroids and cabotegravir/rilpivirine leading to virological failure and development of two-class resistance.

作者信息

Burger David, Wttewaal Eva, Oosterhof Piter, Stalenhoef Janneke

机构信息

Department of Pharmacy, Radboud Institute for Medical Innovations (RIMI), Radboud UMC, Nijmegen.

Department of Internal Medicine.

出版信息

AIDS. 2024 Sep 1;38(11):1728-1729. doi: 10.1097/QAD.0000000000003959. Epub 2024 Aug 1.

DOI:10.1097/QAD.0000000000003959
PMID:39088831
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11296267/
Abstract
摘要