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新冠疫苗接种后脂肪代谢障碍：一例报告。

Lipodystrophy following Covid-19 Vaccination: A case report.

作者信息

Shakarami Mehrnaz, Sinaei Farnaz, Ghaderi Yazdi Bardiya, Ziaadini Bentolhoda

机构信息

Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

Vaccine X. 2024 Jun 22;19:100513. doi: 10.1016/j.jvacx.2024.100513. eCollection 2024 Aug.

DOI:10.1016/j.jvacx.2024.100513
PMID:39091362
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11292498/
Abstract

Lipodystrophy is a medical condition characterized by complete or partial loss of adipose tissue. The etiology of lipoatrophy can be congenital or acquired, including traumatic, iatrogenic, or idiopathic. Rarely, vaccination can cause lipodystrophy. Here, we report the first case of lipodystrophy associated with the COVID-19 Sinopharm vaccine in a 55-year-old woman.

摘要

脂肪营养不良是一种以脂肪组织完全或部分丧失为特征的医学病症。脂肪萎缩的病因可以是先天性的或后天获得性的，包括外伤性、医源性或特发性。疫苗接种极少会导致脂肪营养不良。在此，我们报告首例55岁女性与国药集团新冠疫苗相关的脂肪营养不良病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe3/11292498/b93e791865f5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe3/11292498/297cc915018b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe3/11292498/b93e791865f5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe3/11292498/297cc915018b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe3/11292498/b93e791865f5/gr2.jpg

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本文引用的文献

1
Localized lipoatrophy and inadvertent subcutaneous administration of a COVID-19 vaccine.局部脂肪萎缩和无意中皮下注射 COVID-19 疫苗。
Hum Vaccin Immunother. 2022 Nov 30;18(5):2042136. doi: 10.1080/21645515.2022.2042136. Epub 2022 Mar 8.
2
Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection.与 COVID-19 疫苗接种或 SARS-CoV-2 感染相关的心肌炎、心包炎和心律失常风险。
Nat Med. 2022 Feb;28(2):410-422. doi: 10.1038/s41591-021-01630-0. Epub 2021 Dec 14.
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Unfolding the Mild to Moderate Short-Term Side Effects of Four COVID-19 Vaccines Used in Bahrain: A Cross-Sectional Study.
揭示巴林使用的四种新冠疫苗的轻至中度短期副作用：一项横断面研究
Vaccines (Basel). 2021 Nov 22;9(11):1369. doi: 10.3390/vaccines9111369.
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Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection.新冠病毒疫苗接种后和 SARS-CoV-2 感染后的神经系统并发症。
Nat Med. 2021 Dec;27(12):2144-2153. doi: 10.1038/s41591-021-01556-7. Epub 2021 Oct 25.
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Qualitative Assessment of Early Adverse Effects of Pfizer-BioNTech and Sinopharm COVID-19 Vaccines by Telephone Interviews.通过电话访谈对辉瑞-生物科技公司和国药集团新冠疫苗早期不良反应进行定性评估
Vaccines (Basel). 2021 Aug 26;9(9):950. doi: 10.3390/vaccines9090950.
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Understanding perception and acceptance of Sinopharm vaccine and vaccination against COVID-19 in the UAE.了解阿联酋民众对科兴疫苗的认知和接受程度以及对 COVID-19 的疫苗接种情况。
BMC Public Health. 2021 Aug 30;21(1):1602. doi: 10.1186/s12889-021-11620-z.
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Side effects and perceptions following Sinopharm COVID-19 vaccination.接种科兴新冠疫苗后的副作用和感受。
Int J Infect Dis. 2021 Oct;111:219-226. doi: 10.1016/j.ijid.2021.08.013. Epub 2021 Aug 9.
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Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes: Interim Analysis of 2 Randomized Clinical Trials.新型冠状病毒灭活疫苗在安全性和免疫原性方面的效果：两项随机临床试验的中期分析。
JAMA. 2020 Sep 8;324(10):951-960. doi: 10.1001/jama.2020.15543.
9
Delayed focal lipoatrophy after AS03-adjuvanted influenza A (H1N1) 2009 vaccine.接种 AS03 佐剂季节性流感 A（H1N1）2009 疫苗后出现迟发性局部脂肪萎缩。
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