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一名患有哮喘-慢性阻塞性肺疾病重叠综合征的患者因β2激动剂引发严重震颤。

A severe tremor caused by a beta2 agonist in a patient with asthma-chronic obstructive pulmonary disease overlap.

作者信息

Nakajima Kota, Momo Kenji

机构信息

Department of Pharmacy Izumi Memorial Hospital Tokyo Japan.

Department of Hospital Pharmaceutics School of Pharmacy, Showa University Tokyo Japan.

出版信息

Clin Case Rep. 2024 Jul 31;12(8):e9137. doi: 10.1002/ccr3.9137. eCollection 2024 Aug.

DOI:10.1002/ccr3.9137
PMID:39091622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11291297/
Abstract

A 46-year-old male developed respiratory distress due to asthma-chronic obstructive pulmonary disease overlap and experienced severe tremor caused by beta2 agonist inhalant. We present our successful experience with tizanidine administration.

摘要

一名46岁男性因哮喘-慢性阻塞性肺疾病重叠综合征出现呼吸窘迫,并因吸入β2激动剂而出现严重震颤。我们介绍了使用替扎尼定治疗成功的经验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92df/11291297/6c7eff8fc595/CCR3-12-e9137-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92df/11291297/b304bfa94694/CCR3-12-e9137-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92df/11291297/6c7eff8fc595/CCR3-12-e9137-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92df/11291297/b304bfa94694/CCR3-12-e9137-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92df/11291297/6c7eff8fc595/CCR3-12-e9137-g002.jpg

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Parkinson's Disease and Parkinsonism.帕金森病和帕金森综合征。
Am J Med. 2019 Jul;132(7):802-807. doi: 10.1016/j.amjmed.2019.03.001. Epub 2019 Mar 16.
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Lower metabolic clearance of tizanidine in Japanese subjects.替扎尼定在日本受试者中的代谢清除率较低。
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Tremor and β(2)-adrenergic agents: is it a real clinical problem?震颤与β(2)-肾上腺素能制剂:这是一个真正的临床问题吗?
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Tizanidine-induced hypotension in patients with liver cirrhosis.肝硬化患者中替扎尼定诱发的低血压
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Drug interaction of tizanidine and ciprofloxacin: case report.替扎尼定与环丙沙星的药物相互作用:病例报告
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Practice parameter: therapies for essential tremor [RETIRED]: report of the Quality Standards Subcommittee of the American Academy of Neurology.实践参数:特发性震颤的治疗方法[已退休]:美国神经病学学会质量标准小组委员会报告
Neurology. 2005 Jun 28;64(12):2008-20. doi: 10.1212/01.WNL.0000163769.28552.CD. Epub 2005 Jun 22.
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Drug interaction of tizanidine and fluvoxamine.替扎尼定与氟伏沙明的药物相互作用。
Clin Pharmacol Ther. 2004 Nov;76(5):509-10. doi: 10.1016/j.clpt.2004.08.003.
10
Tizanidine is mainly metabolized by cytochrome p450 1A2 in vitro.替扎尼定在体外主要由细胞色素P450 1A2代谢。
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