Wenzel M, Heinrich M, Schmidt C
Pharmatherapeutica. 1985;4(6):351-5.
In a study of 60 patients undergoing elective colonic surgery peri-operative infection prophylaxis by the "one-shot' method was compared with that of 48-hour duration. The antibacterial agents used were ornidazole and gentamicin. Considering the patient population as a whole, no significant differences were found in the results. All the infectious complications which occurred post-operatively were due to bacterial contamination by aerobic pathogens. No anaerobic pathogens were detected in any of the cases.
在一项针对60例接受择期结肠手术患者的研究中,将采用“单次给药”方法进行围手术期感染预防与持续48小时的预防方法进行了比较。所使用的抗菌药物为奥硝唑和庆大霉素。从总体患者群体来看,结果未发现显著差异。所有术后发生的感染并发症均由需氧病原体的细菌污染所致。在任何病例中均未检测到厌氧病原体。