Asmamaw Getahun, Shimelis Tekalign, Tewuhibo Dinksew, Bitew Teshome, Ayenew Wondim
Department of Social and Administrative Pharmacy, Directorate of Pharmacy Education and Clinical Services, Arba Minch University, Arba Minch, Ethiopia.
Directorate of Pharmacy Education and Clinical Services, Arba Minch University, Arba Minch, Ethiopia.
SAGE Open Med. 2024 Jul 30;12:20503121241266318. doi: 10.1177/20503121241266318. eCollection 2024.
This study aims to assess access to essential medicines used in the management of noncommunicable diseases through analysis of the availability, prices, and affordability of these essential medicines in Arba Minch town, Gamo Zone, Southern Ethiopia.
A cross-sectional design was carried out using the World Health Organization/health action international methodology between 2 March and 2 May 2023, within public and private healthcare facilities located in Arba Minch town, Southern Ethiopia. The median price ratio served as a metric. Statistical tests like the Shapiro-Wilk and Kolmogorov-Smirnov were utilized to assess the normal distribution of price data. The Wilcoxon-Mann-Whitney U test was also employed to compare median buyer's prices (patient prices) between public and private healthcare institutions. Treatment affordability was determined by estimating the number of days' wages required by the lowest-paid government employee in Ethiopia to afford the prescribed medication regimen.
Among 23 health facilities surveyed, the pooled availability of essential medicine used in the management of noncommunicable diseases was 18.7% (range: 0%-30.1%), with the public and private facilities contributing 16.3% and 38.3%, respectively. The overall percentage of availability originator brand versions was 1.1% for overall health sectors, 0.6% for public sectors, and 1.2% for private sectors. The overall percent availability of lowest price generics was 36.2% (range: 0%-26.2%; public: 32.0%; private: 37.1%). Only seven lowest price generics satisfied the World Health Organization target of 80% and above. The overall median price of lowest price generic medicines in private was two times higher than in public sectors. The top five median price scorers were amlodipine, furosemide, insulin, beclomethasone, and salbutamol. The Mann-Whitney U test showed that 11.6% of lowest price generics medicines had a statistically significant median price disparity between the public and private sectors ( < 0.05). The overall percent of unaffordability was found to be 100.0%, (public: 70.4; private: 100.0%).
This study revealed the limited availability and potential financial burdens on patients seeking essential noncommunicable disease medications. Limited availability suggests the need for better supply chain management and consistent stock availability. The price disparities and affordability challenges identified underscore the necessity for policy interventions such as price regulation and subsidized programs to ensure equitable access to essential noncommunicable disease medications in Arba Minch town, Southern Ethiopia.
本研究旨在通过分析埃塞俄比亚南部加莫地区阿尔巴明奇镇这些基本药物的可及性、价格和可负担性,评估用于非传染性疾病管理的基本药物的获取情况。
于2023年3月2日至5月2日期间,采用世界卫生组织/国际卫生行动方法,在埃塞俄比亚南部阿尔巴明奇镇的公立和私立医疗机构中开展横断面设计。中位数价格比作为一项指标。使用夏皮罗-威尔克检验和柯尔莫哥洛夫-斯米尔诺夫检验等统计检验来评估价格数据的正态分布。还采用威尔科克森-曼-惠特尼U检验来比较公立和私立医疗机构中购买者的中位数价格(患者价格)。通过估计埃塞俄比亚收入最低的政府雇员支付规定药物治疗方案所需的天数工资来确定治疗的可负担性。
在接受调查 的23家医疗机构中,用于非传染性疾病管理的基本药物的综合可及率为18.7%(范围:0%-30.1%),其中公立和私立机构分别为16.3%和38.3%。总体卫生部门中原创品牌版本的总体可及率为1.1%,公共部门为0.6%,私营部门为1.2%。最低价格仿制药的总体可及率为36.2%(范围:0%-26.2%;公立:32.0%;私立:37.1%)。只有七种最低价格仿制药达到了世界卫生组织80%及以上的目标。私立机构中最低价格仿制药的总体中位数价格比公立机构高出两倍。中位数价格得分最高的五种药物是氨氯地平、呋塞米、胰岛素、倍氯米松和沙丁胺醇。曼-惠特尼U检验显示,11.6%的最低价格仿制药在公立和私立部门之间存在统计学上显著的中位数价格差异(<0.05)。总体不可负担率为100.0%(公立:70.4%;私立:100.0%)。
本研究揭示了寻求基本非传染性疾病药物的患者可及性有限以及潜在的经济负担。可及性有限表明需要更好的供应链管理和持续的库存供应。所发现的价格差异和可负担性挑战突出了价格监管和补贴计划等政策干预措施的必要性,以确保埃塞俄比亚南部阿尔巴明奇镇的居民能够公平获取基本非传染性疾病药物。