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水源性疾病的演变:以巴基斯坦开伯尔-普赫图赫瓦省为例

Evolution of waterborne diseases: A case study of Khyber Pakhtunkhwa, Pakistan.

作者信息

Atif Muhammad, Ayub Gohar, Shakoor Fazal, Farooq Muhammad, Iqbal Muhammad, Zaman Qamruz, Ilyas Muhammad

机构信息

Department of Statistics, University of Peshawar, Peshawar, Pakistan.

Department of Mathematics and Statistics, University of Swat, Swat, Pakistan.

出版信息

SAGE Open Med. 2024 Jul 31;12:20503121241263032. doi: 10.1177/20503121241263032. eCollection 2024.

Abstract

OBJECTIVES

In Pakistan, the degradation of drinking water quality is exacerbated by the increasing population size and rapid industrialization. Contaminated water serves as the predominant source of numerous diseases, including diarrhea, gastroenteritis, and typhoid. This article explores the evolution of waterborne diseases across 21 districts of the Khyber Pakhtunkhwa province in Pakistan by monitoring changes in the clustering solutions.

METHODS

The data employed in this study were sourced from 21 districts of KP by the Director-General Health Services. Cluster analysis was utilized to uncover patterns in waterborne disease incidence, while principal component analysis was employed to reveal underlying patterns and reduce dimensionality. Additionally, the MONItoring Clusters (MONIC) framework was applied for change detection, facilitating the identification of significant shifts in disease patterns over time and aiding in the understanding of temporal dynamics.

RESULTS

Our analysis indicates that two clusters survived consistently over time, while other clusters exhibited inconsistency. Profiling of the surviving clusters (C → C → C → C) suggests a gradual increase in cases of bloody diarrhea in the Swat Valley, Hangu, Karak, and Lakki Marwat regions. Similarly, profiling of the surviving clusters (⊙→ C → C → C) suggests an increase in the acute watery diarrhea (non-cholera) and typhoid fever in the regions of Peshawar, Nowshera, and Swabi.

CONCLUSION

The findings of this study hold significant importance as they pinpoint the most vulnerable regions for various waterborne diseases. These insights offer valuable guidance to policymakers and health officials, empowering them to implement effective measures for controlling waterborne diseases in the respective regions of Khyber Pakhtunkhwa, Pakistan.

摘要

目标

在巴基斯坦,人口规模的不断增长和快速工业化加剧了饮用水质量的恶化。受污染的水是包括腹泻、肠胃炎和伤寒在内的众多疾病的主要来源。本文通过监测聚类解决方案的变化,探讨了巴基斯坦开伯尔-普赫图赫瓦省21个地区水源性疾病的演变情况。

方法

本研究使用的数据由卫生服务总局提供,来自开伯尔-普赫图赫瓦省的21个地区。聚类分析用于发现水源性疾病发病率的模式,而主成分分析则用于揭示潜在模式并降低维度。此外,监测聚类(MONIC)框架被应用于变化检测,有助于识别疾病模式随时间的显著变化,并有助于理解时间动态。

结果

我们的分析表明,有两个聚类随时间一直存在,而其他聚类则表现出不一致性。对持续存在的聚类(C→C→C→C)进行剖析表明,斯瓦特山谷、汉古、卡拉奇和拉基马瓦特地区的血性腹泻病例逐渐增加。同样,对持续存在的聚类(⊙→C→C→C)进行剖析表明,白沙瓦、瑙谢拉和斯瓦比地区的急性水样腹泻(非霍乱)和伤寒热有所增加。

结论

本研究的结果具有重要意义,因为它们指出了各种水源性疾病最脆弱的地区。这些见解为政策制定者和卫生官员提供了宝贵的指导,使他们能够在巴基斯坦开伯尔-普赫图赫瓦省的各个地区采取有效措施控制水源性疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68df/11292715/418d6e057f57/10.1177_20503121241263032-fig1.jpg

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