The National Key Laboratory of Water Disaster Prevention, Hohai University, Nanjing, 210098, China.
College of Hydrology and Water Resources, Hohai University, Nanjing, 210098, China.
Environ Sci Pollut Res Int. 2024 Aug;31(38):50333-50346. doi: 10.1007/s11356-024-34580-4. Epub 2024 Aug 2.
17β-Estradiol (E2) is a novel micro-pollutant that is widely distributed in aquatic sediments and has a universal toxicological effect on aquatic organisms. However, its ecological impact on aquatic microorganisms is not yet clear. In this study, we designed a simulation system for oligotrophic water deposition in the laboratory, analyzed the impact of different concentrations of E2 pollution on the carbon metabolism activity (carbon gas emission rate) of water microorganisms. Based on high-throughput sequencing results, we revealed the impact of E2 pollution on the community structure succession and metabolic function of bacteria, archaea, and methanogens in the simulated system, explored the impact mechanism of E2 pollution on microbial carbon metabolism in water bodies. Our results suggested that E2 significantly impacts the bacterial and archaeal community rather than the methanogen community, thereby indirectly inhibiting methane production. The achievements will bridge the theoretical gap between estrogen metabolism and carbon metabolism in sedimentary environments and contribute to enriching the ecological toxicology theory of steroid estrogen.
17β-雌二醇（E2）是一种新型的微污染物，广泛分布于水生生境的沉积物中，对水生生物具有普遍的毒理学效应。然而，其对水生微生物的生态影响尚不清楚。在本研究中，我们设计了一个实验室模拟贫营养水沉积的系统，分析了不同浓度 E2 污染对水微生物碳代谢活性（碳气体排放速率）的影响。基于高通量测序结果，揭示了 E2 污染对模拟系统中细菌、古菌和产甲烷菌的群落结构演替和代谢功能的影响，探讨了 E2 污染对水体微生物碳代谢的影响机制。研究结果表明，E2 显著影响细菌和古菌群落，而不是产甲烷菌群落，从而间接抑制甲烷生成。该研究成果将填补雌激素代谢与沉积环境中碳代谢之间的理论空白，丰富甾体雌激素的生态毒理学理论。
