使用脆弱性指数评估随机临床试验结果的稳健性。 - Suppr

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Assessing robustness of results of randomised clinical trials using Fragility Index.

作者信息

Nainar S M H

机构信息

Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.

出版信息

Eur Arch Paediatr Dent. 2024 Oct;25(5):777-778. doi: 10.1007/s40368-024-00930-6. Epub 2024 Aug 2.

DOI:10.1007/s40368-024-00930-6

PMID:39093533

Abstract

摘要

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本文引用的文献

Fragility index: tips and tricks for interpretation.脆弱性指数：解读技巧与窍门

Eur Heart J Acute Cardiovasc Care. 2024 May 28;13(5):446-448. doi: 10.1093/ehjacc/zuae055.

Editorial Commentary: The Statistical Fragility Index of Medical Trials Is Low By Design: Critical Evaluation of Confidence Intervals Is Required.社论评论：医学试验的统计脆弱指数低是设计使然：需要对置信区间进行批判性评估。

Arthroscopy. 2024 Mar;40(3):1006-1008. doi: 10.1016/j.arthro.2023.10.010. Epub 2024 Jan 12.

Empirical assessment of fragility index based on a large database of clinical studies in the Cochrane Library.基于 Cochrane 图书馆中大量临床研究数据库的脆性指数的实证评估。

J Eval Clin Pract. 2023 Mar;29(2):359-370. doi: 10.1111/jep.13787. Epub 2022 Nov 2.

Statistical robustness of randomized controlled trials in high-impact journals has improved but was low across medical specialties.高影响力期刊中随机对照试验的统计稳健性有所提高，但在各医学专科中仍处于较低水平。

J Clin Epidemiol. 2022 Oct;150:165-170. doi: 10.1016/j.jclinepi.2022.07.001. Epub 2022 Jul 9.

Consideration Regarding the Analysis of Randomized Controlled Trials in the Era of Evidence-based Medicine.考虑在循证医学时代分析随机对照试验。

J Cardiovasc Pharmacol. 2022 May 1;79(5):605-619. doi: 10.1097/FJC.0000000000001215.

On clinical trial fragility due to patients lost to follow up.由于患者失访导致的临床试验脆弱性。

BMC Med Res Methodol. 2021 Nov 20;21(1):254. doi: 10.1186/s12874-021-01446-z.

The fragility index can be used for sample size calculations in clinical trials.脆性指数可用于临床试验的样本量计算。

J Clin Epidemiol. 2021 Nov;139:199-209. doi: 10.1016/j.jclinepi.2021.08.010. Epub 2021 Aug 15.

The Fragility Index for Assessing the Robustness of the Statistically Significant Results of Experimental Clinical Studies.用于评估实验性临床研究统计学显著结果稳健性的脆弱性指数

J Gen Intern Med. 2022 Jan;37(1):206-211. doi: 10.1007/s11606-021-06999-9. Epub 2021 Aug 6.

The statistical significance of meta-analyses is frequently fragile: definition of a fragility index for meta-analyses.荟萃分析的统计学意义通常很脆弱：荟萃分析脆弱指数的定义。

J Clin Epidemiol. 2019 Jul;111:32-40. doi: 10.1016/j.jclinepi.2019.03.012. Epub 2019 Mar 30.

The Fragility Index in a Cohort of Pediatric Randomized Controlled Trials.一组儿科随机对照试验中的脆弱性指数

J Clin Med. 2017 Aug 14;6(8):79. doi: 10.3390/jcm6080079.

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