College of Environmental Science and Engineering and Key Laboratory of Environmental Biology and Pollution Control (Ministry of Education), Hunan University, Changsha 410082, China.
Fujian Provincial Key Laboratory of Soil Environmental Health and Regulation, College of Resources and Environment, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
J Environ Sci (China). 2025 Feb;148:243-262. doi: 10.1016/j.jes.2024.01.005. Epub 2024 Jan 30.
Because of the recent widespread usage of antibiotics, the acquisition and dissemination of antibiotic-resistance genes (ARGs) were prevalent in the majority of habitats. Generally, the biological wastewater treatment processes used in wastewater treatment plants have a limited efficiencies of antibiotics resistant bacteria (ARB) disinfection and ARGs degradation and even promote the proliferation of ARGs. Problematically, ARB and ARGs in effluent pose potential risks if they are not further treated. Photocatalytic oxidation is considered a promising disinfection technology, where the photocatalytic process generates many free radicals that enhance the interaction between light and deoxyribonucleic acid (DNA) for ARB elimination and subsequent degradation of ARGs. This review aims to illustrate the progress of photocatalytic oxidation technology for removing antibiotics resistant (AR) from wastewater in recent years. We discuss the sources and transfer of ARGs in wastewater. The overall removal efficiencies of ultraviolet radiation (UV)/chlorination, UV/ozone, UV/HO, and UV/sulfate-radical based system for ARB and ARGs, as well as the experimental parameters and removal mechanisms, are systematically discussed. The contribution of photocatalytic materials based on TiO and g-CN to the inactivation of ARB and degradation of ARGs is highlighted, producing many free radicals to attack ARB and ARGs while effectively limiting the horizontal gene transfer (HGT) in wastewater. Finally, based on the reviewed studies, future research directions are proposed to realize specific photocatalytic oxidation technology applications and overcome current challenges.
由于抗生素的广泛使用，抗生素耐药基因（ARGs）在大多数环境中都普遍存在于获取和传播。一般来说，污水处理厂使用的生物污水处理工艺对耐抗生素细菌（ARB）的消毒和 ARGs 降解的效率有限，甚至会促进 ARGs 的增殖。如果不进一步处理，污水中的 ARB 和 ARGs 会带来潜在的风险。光催化氧化被认为是一种很有前途的消毒技术，其中光催化过程会产生许多自由基，增强光与脱氧核糖核酸（DNA）的相互作用，从而消除 ARB 并随后降解 ARGs。本文旨在阐述近年来光催化氧化技术去除废水中抗生素耐药性（AR）的研究进展。我们讨论了废水中原位基因转移的来源和转移。系统讨论了紫外线辐射（UV）/氯化、UV/臭氧、UV/HO 和基于 UV/硫酸盐自由基的系统对 ARB 和 ARGs 的整体去除效率，以及实验参数和去除机制。强调了基于 TiO 和 g-CN 的光催化材料对 ARB 的灭活和 ARGs 的降解的贡献，产生了许多自由基来攻击 ARB 和 ARGs，同时有效地限制了废水中的水平基因转移（HGT）。最后，根据综述研究，提出了未来的研究方向，以实现特定的光催化氧化技术应用，并克服当前的挑战。
