Suppr超能文献

发展中国家儿童行完全修复法洛四联症时采用经食管超声心动图指导的暖血心脏不停跳手术的早期结果

Early outcomes of experience warm surgery in children undergoing complete repair of tetralogy of Fallot in developing countries.

机构信息

University Children's Hospital, Damascus University, Damascus, Syrian Arab Republic.

出版信息

BMC Pediatr. 2024 Aug 3;24(1):499. doi: 10.1186/s12887-024-04976-9.

Abstract

OBJECTIVES

While significant evidence supports the benefits of normothermic cardiopulmonary bypass (NCPB) over hypothermic techniques, many institutions in developing countries, including ours, continue to employ hypothermic methods. This study aimed to assess the early postoperative outcomes of normothermic cardiopulmonary bypass (NCPB) for complete surgical repair via the Tetralogy of Fallot (TOF) within our national context.

METHODS

We conducted this study in the Pediatric Cardiac Intensive Care Unit (PCICU) at the University Children's Hospital. One hundred patients who underwent complete TOF repair were enrolled and categorized into two groups: the normothermic group (n = 50, temperature 35-37 °C) and the moderate hypothermic group (n = 50, temperature 28-32 °C). We evaluated mortality, morbidity, and postoperative complications in the PCICU as outcome measures.

RESULTS

The demographic characteristics were similar between the two groups. However, the cardiopulmonary bypass (CPB) time and aortic cross-clamp (ACC) time were notably longer in the hypothermic group. The study recorded seven deaths, yielding an overall mortality rate of 7%. No significant differences were observed between the two groups concerning mortality, morbidity, or postoperative complications in the PCICU.

CONCLUSIONS

Our findings suggest that normothermic procedures, while not demonstrably effective, are safe for pediatric cardiac surgery. Further research is warranted to substantiate and endorse the adoption of this technique.

摘要

目的

尽管有大量证据支持常温体外循环(NCPB)优于低温技术,但包括我们医院在内的许多发展中国家的机构仍在使用低温方法。本研究旨在评估我们国家常温体外循环(NCPB)在完全通过法洛四联症(TOF)进行心脏手术修复中的早期术后结果。

方法

我们在大学儿童医院的儿科心脏重症监护病房(PCICU)进行了这项研究。共纳入了 100 名接受完全 TOF 修复的患者,并将他们分为两组:常温组(n=50,温度 35-37°C)和中度低温组(n=50,温度 28-32°C)。我们评估了 PCICU 中的死亡率、发病率和术后并发症作为结局指标。

结果

两组的人口统计学特征相似。然而,低温组的体外循环(CPB)时间和主动脉阻断(ACC)时间明显更长。该研究记录了 7 例死亡,总死亡率为 7%。两组在 PCICU 中的死亡率、发病率或术后并发症方面无显著差异。

结论

我们的发现表明,常温手术虽然没有明显的效果,但对儿科心脏手术是安全的。需要进一步的研究来证实和支持采用这种技术。

相似文献

5
Staged Versus Complete Repair in the Symptomatic Neonate With Tetralogy of Fallot.
Ann Thorac Surg. 2020 Mar;109(3):802-808. doi: 10.1016/j.athoracsur.2019.10.013. Epub 2019 Nov 26.
6
22q11.2 Deletion syndrome is associated with perioperative outcome in tetralogy of Fallot.
J Thorac Cardiovasc Surg. 2013 Oct;146(4):868-73. doi: 10.1016/j.jtcvs.2012.12.028. Epub 2013 Jan 11.
9
Results of elective repair at 6 months or younger in 277 patients with tetralogy of Fallot: a 14-year experience at a single center.
J Thorac Cardiovasc Surg. 2014 Feb;147(2):713-7. doi: 10.1016/j.jtcvs.2013.03.033. Epub 2013 Apr 18.
10
Primary tetralogy of Fallot repair: predictors of intensive care unit morbidity.
Asian Cardiovasc Thorac Ann. 2014 Sep;22(7):794-9. doi: 10.1177/0218492313513773. Epub 2013 Nov 22.

本文引用的文献

1
Outcome after surgical repair of tetralogy of Fallot: A systematic review and meta-analysis.
J Thorac Cardiovasc Surg. 2020 Jan;159(1):220-236.e8. doi: 10.1016/j.jtcvs.2019.08.127. Epub 2019 Sep 25.
2
Safety of Normothermic Cardiopulmonary Bypass in Pediatric Cardiac Surgery: A System Review and Meta-Analysis.
Front Pediatr. 2021 Dec 14;9:757551. doi: 10.3389/fped.2021.757551. eCollection 2021.
3
Temperature management on cardiopulmonary bypass: Is it standardised across Great Britain and Ireland?
Perfusion. 2022 Apr;37(3):221-228. doi: 10.1177/0267659121995996. Epub 2021 Feb 26.
4
Normothermia versus Hypothermia during Cardiopulmonary Bypass in Cases of Repair of Atrioventricular Septal Defect.
Anesth Essays Res. 2020 Jan-Mar;14(1):112-118. doi: 10.4103/aer.AER_123_19. Epub 2020 Feb 14.
5
Normothermic versus hypothermic cardiopulmonary bypass in low-risk paediatric heart surgery: a randomised controlled trial.
Heart. 2019 Mar;105(6):455-464. doi: 10.1136/heartjnl-2018-313567. Epub 2018 Oct 15.
7
8
The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2018 Update on Outcomes and Quality.
Ann Thorac Surg. 2018 Mar;105(3):680-689. doi: 10.1016/j.athoracsur.2018.01.001. Epub 2018 Jan 11.
9
Rationale for Implementation of Warm Cardiac Surgery in Pediatrics.
Front Pediatr. 2016 May 6;4:43. doi: 10.3389/fped.2016.00043. eCollection 2016.
10
Normothermia for pediatric and congenital heart surgery: an expanded horizon.
Front Pediatr. 2015 Apr 28;3:23. doi: 10.3389/fped.2015.00023. eCollection 2015.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验