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本文引用的文献

1
Outcome after surgical repair of tetralogy of Fallot: A systematic review and meta-analysis.法洛四联症手术修复后的结果:一项系统评价与荟萃分析。
J Thorac Cardiovasc Surg. 2020 Jan;159(1):220-236.e8. doi: 10.1016/j.jtcvs.2019.08.127. Epub 2019 Sep 25.
2
Safety of Normothermic Cardiopulmonary Bypass in Pediatric Cardiac Surgery: A System Review and Meta-Analysis.小儿心脏手术中常温体外循环的安全性:一项系统评价和荟萃分析
Front Pediatr. 2021 Dec 14;9:757551. doi: 10.3389/fped.2021.757551. eCollection 2021.
3
Temperature management on cardiopulmonary bypass: Is it standardised across Great Britain and Ireland?体外循环中的体温管理:英国和爱尔兰各地是否标准化?
Perfusion. 2022 Apr;37(3):221-228. doi: 10.1177/0267659121995996. Epub 2021 Feb 26.
4
Normothermia versus Hypothermia during Cardiopulmonary Bypass in Cases of Repair of Atrioventricular Septal Defect.房室间隔缺损修复术中体外循环期间体温正常与体温过低的比较。
Anesth Essays Res. 2020 Jan-Mar;14(1):112-118. doi: 10.4103/aer.AER_123_19. Epub 2020 Feb 14.
5
Normothermic versus hypothermic cardiopulmonary bypass in low-risk paediatric heart surgery: a randomised controlled trial.常温与低温体外循环在低危儿科心脏手术中的应用:一项随机对照试验。
Heart. 2019 Mar;105(6):455-464. doi: 10.1136/heartjnl-2018-313567. Epub 2018 Oct 15.
6
Comparison of Early Outcomes for Normothermic and Hypothermic Cardiopulmonary Bypass in Children Undergoing Congenital Heart Surgery.先天性心脏病手术患儿中常温与低温体外循环早期结果的比较。
Front Pediatr. 2018 Aug 17;6:219. doi: 10.3389/fped.2018.00219. eCollection 2018.
7
Predictors of Length of Hospital Stay After Complete Repair for Tetralogy of Fallot: A Prospective Cohort Study.法洛四联症完全修复术后住院时间的预测因素:一项前瞻性队列研究。
J Am Heart Assoc. 2018 May 16;7(11):e008719. doi: 10.1161/JAHA.118.008719.
8
The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2018 Update on Outcomes and Quality.美国胸外科协会先天性心脏病数据库:2018 年结局和质量更新。
Ann Thorac Surg. 2018 Mar;105(3):680-689. doi: 10.1016/j.athoracsur.2018.01.001. Epub 2018 Jan 11.
9
Rationale for Implementation of Warm Cardiac Surgery in Pediatrics.儿科心脏手术中应用温血心脏停搏液的理由。
Front Pediatr. 2016 May 6;4:43. doi: 10.3389/fped.2016.00043. eCollection 2016.
10
Normothermia for pediatric and congenital heart surgery: an expanded horizon.儿科和先天性心脏病手术中的体温正常化:更广阔的前景。
Front Pediatr. 2015 Apr 28;3:23. doi: 10.3389/fped.2015.00023. eCollection 2015.

发展中国家儿童行完全修复法洛四联症时采用经食管超声心动图指导的暖血心脏不停跳手术的早期结果

Early outcomes of experience warm surgery in children undergoing complete repair of tetralogy of Fallot in developing countries.

机构信息

University Children's Hospital, Damascus University, Damascus, Syrian Arab Republic.

出版信息

BMC Pediatr. 2024 Aug 3;24(1):499. doi: 10.1186/s12887-024-04976-9.

DOI:10.1186/s12887-024-04976-9
PMID:39097678
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11297559/
Abstract

OBJECTIVES

While significant evidence supports the benefits of normothermic cardiopulmonary bypass (NCPB) over hypothermic techniques, many institutions in developing countries, including ours, continue to employ hypothermic methods. This study aimed to assess the early postoperative outcomes of normothermic cardiopulmonary bypass (NCPB) for complete surgical repair via the Tetralogy of Fallot (TOF) within our national context.

METHODS

We conducted this study in the Pediatric Cardiac Intensive Care Unit (PCICU) at the University Children's Hospital. One hundred patients who underwent complete TOF repair were enrolled and categorized into two groups: the normothermic group (n = 50, temperature 35-37 °C) and the moderate hypothermic group (n = 50, temperature 28-32 °C). We evaluated mortality, morbidity, and postoperative complications in the PCICU as outcome measures.

RESULTS

The demographic characteristics were similar between the two groups. However, the cardiopulmonary bypass (CPB) time and aortic cross-clamp (ACC) time were notably longer in the hypothermic group. The study recorded seven deaths, yielding an overall mortality rate of 7%. No significant differences were observed between the two groups concerning mortality, morbidity, or postoperative complications in the PCICU.

CONCLUSIONS

Our findings suggest that normothermic procedures, while not demonstrably effective, are safe for pediatric cardiac surgery. Further research is warranted to substantiate and endorse the adoption of this technique.

摘要

目的

尽管有大量证据支持常温体外循环(NCPB)优于低温技术,但包括我们医院在内的许多发展中国家的机构仍在使用低温方法。本研究旨在评估我们国家常温体外循环(NCPB)在完全通过法洛四联症(TOF)进行心脏手术修复中的早期术后结果。

方法

我们在大学儿童医院的儿科心脏重症监护病房(PCICU)进行了这项研究。共纳入了 100 名接受完全 TOF 修复的患者,并将他们分为两组:常温组(n=50,温度 35-37°C)和中度低温组(n=50,温度 28-32°C)。我们评估了 PCICU 中的死亡率、发病率和术后并发症作为结局指标。

结果

两组的人口统计学特征相似。然而,低温组的体外循环(CPB)时间和主动脉阻断(ACC)时间明显更长。该研究记录了 7 例死亡,总死亡率为 7%。两组在 PCICU 中的死亡率、发病率或术后并发症方面无显著差异。

结论

我们的发现表明,常温手术虽然没有明显的效果,但对儿科心脏手术是安全的。需要进一步的研究来证实和支持采用这种技术。