体育活动对肥胖老年女性游离脂肪酸、胰岛素抵抗及血压的影响。
Effect of physical activity on free fatty acids, insulin resistance, and blood pressure in obese older women.
作者信息
Son Woo-Hyeon, Ha Min-Seong, Park Tae-Jin
机构信息
Institute of Convergence Bio-Health, Dong-A University, Busan, Republic of Korea.
Laboratory of Sports Conditioning: Nutrition Biochemistry and Neuroscience, Department of Sport, College of the Arts and Sports, University of Seoul, Seoul, Republic of Korea.
出版信息
Phys Act Nutr. 2024 Jun;28(2):1-6. doi: 10.20463/pan.2024.0009. Epub 2024 Jun 30.
PURPOSE
Obesity is characterized by a progressive increase in body fat accompanied by insulin resistance (IR) and elevated blood pressure (BP), and presents significant health risks, particularly in aged individuals. This study aimed to evaluate the effects of physical activity (PA) on free fatty acid (FFA) levels, IR, and BP in obese older women.
METHODS
Twenty-three participants were randomly assigned to either the control group (CON, n = 11) or the physical activity group (PA, n = 12). The PA group was provided with a target of achieving >7,000 steps/day for 5 days each week. Body composition, FFA levels, IR, and BP were measured at pre- and post- of the 12-week intervention.
RESULTS
The analysis revealed a statistically significant interaction between FFA (p < 0.01), IR (p < 0.01), and SBP (p < 0.001). FFA (p < 0.5), IR (p < 0.5), and systolic blood pressure (SBP) (p < 0.01) were significantly decreased in the PA group compared to those in the CON group, which showed no significant changes in FFA, IR, and SBP.
CONCLUSION
PA significantly decreased FFA, IR, and SBP in older women with obesity. Therefore, PA is an effective intervention for the prevention and management of obesity and cardiovascular diseases in obese older women.
目的
肥胖的特征是体脂逐渐增加，伴有胰岛素抵抗（IR）和血压（BP）升高，存在重大健康风险，尤其是在老年个体中。本研究旨在评估体育活动（PA）对肥胖老年女性游离脂肪酸（FFA）水平、IR和BP的影响。
方法
23名参与者被随机分为对照组（CON，n = 11）或体育活动组（PA，n = 12）。PA组的目标是每周5天每天步数超过7000步。在为期12周的干预前后测量身体成分、FFA水平、IR和BP。
结果
分析显示FFA（p < 0.01）、IR（p < 0.01）和收缩压（SBP）（p < 0.001）之间存在统计学显著的交互作用。与CON组相比，PA组的FFA（p < 0.5）、IR（p < 0.5）和收缩压（SBP）（p < 0.01）显著降低，而CON组的FFA、IR和SBP无显著变化。
结论
PA显著降低了肥胖老年女性的FFA、IR和SBP。因此，PA是预防和管理肥胖老年女性肥胖及心血管疾病的有效干预措施。
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