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罕见的合并情况:一名患有法洛四联症的成年人出现脑脓肿

A Rare Confluence: Brain Abscess in an Adult With Tetralogy of Fallot.

作者信息

Gupta Palak, Singh Harpratap, Vashisht Naveya, Dhingra Gurneet Singh, Sharma Vanshdeep

机构信息

Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Ambala, IND.

Medicine, Subharti Medical College, Meerut, IND.

出版信息

Cureus. 2024 Jul 4;16(7):e63860. doi: 10.7759/cureus.63860. eCollection 2024 Jul.

DOI:10.7759/cureus.63860
PMID:39100046
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11297518/
Abstract

Tetralogy of Fallot (TOF) is a common congenital heart disease (CHD) characterized by four distinct cardiac abnormalities. Brain abscess, though rare, is a life-threatening complication in patients with cyanotic congenital heart disease (CCHD), including TOF. This case report describes a 24-year-old female with unrepaired TOF who presented with symptoms of a brain abscess, including altered sensorium, fever, projectile vomiting, and headache. Diagnostic imaging with non-contrast-enhanced computed tomography (NCCT) revealed a well-defined hypodense lesion with a midline shift, prompting urgent drainage of the abscess. Subsequent cultures of the pus material identified  as the causative agent, and the patient was maintained on antibiotics. This case highlights the importance of early diagnosis and surgical repair of TOF to prevent severe complications such as brain abscess, thereby reducing morbidity and mortality.

摘要

法洛四联症(TOF)是一种常见的先天性心脏病(CHD),其特征为四种不同的心脏异常。脑脓肿虽然罕见,但在包括TOF在内的青紫型先天性心脏病(CCHD)患者中是一种危及生命的并发症。本病例报告描述了一名24岁未接受修复手术的TOF女性患者,她出现了脑脓肿的症状,包括意识改变、发热、喷射性呕吐和头痛。非增强计算机断层扫描(NCCT)诊断成像显示一个边界清晰的低密度病变并有中线移位,促使紧急引流脓肿。随后对脓液样本进行培养,确定了病原体,患者接受抗生素治疗。本病例强调了TOF早期诊断和手术修复以预防诸如脑脓肿等严重并发症的重要性,从而降低发病率和死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/357f/11297518/3d0a4fe2bd55/cureus-0016-00000063860-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/357f/11297518/b7b4622de31a/cureus-0016-00000063860-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/357f/11297518/412ca2238adf/cureus-0016-00000063860-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/357f/11297518/3d0a4fe2bd55/cureus-0016-00000063860-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/357f/11297518/b7b4622de31a/cureus-0016-00000063860-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/357f/11297518/412ca2238adf/cureus-0016-00000063860-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/357f/11297518/3d0a4fe2bd55/cureus-0016-00000063860-i03.jpg

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本文引用的文献

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Recurrent Brain Abscess in a Child With Cyanotic Congenital Heart Disease.患有青紫型先天性心脏病儿童的复发性脑脓肿
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J Am Heart Assoc. 2018 Feb 8;7(4):e007907. doi: 10.1161/JAHA.117.007907.
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