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生物膜可吸收钉固定术联合基质诱导自体软骨细胞移植治疗软骨缺损

Absorbable Nail Fixation of Biologic Membrane for Treatment of Cartilage Defects by Matrix-Induced Autologous Chondrocyte Implantation.

作者信息

Liu Zhenlong, Ye Fanhao, Ao Yingfang, Gong Xi

机构信息

Beijing Key Laboratory of Sports Injuries, Beijing, China.

Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.

出版信息

Arthrosc Tech. 2024 Apr 22;13(7):102984. doi: 10.1016/j.eats.2024.102984. eCollection 2024 Jul.

DOI:10.1016/j.eats.2024.102984
PMID:39100269
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11293332/
Abstract

Injuries to articular cartilage caused by a variety of factors are common clinically and can impair quality of life and lead to long-term dysfunction in a manner similar to osteoarthritis, which has led to the development of various repair techniques for articular cartilage injury. Although each technique has its own limitations and advantages, matrix-induced autologous chondrocyte implantation has been widely used and achieved good clinical results. We present a technique for fixing biofilms with absorbable nails with a "Roman column structure" as the main structure. The described technique allows stable immobilization of the biofilm while ensuring that subsequent cartilage damage repair can proceed smoothly.

摘要

由多种因素引起的关节软骨损伤在临床上很常见，会损害生活质量并导致类似于骨关节炎的长期功能障碍，这促使了各种关节软骨损伤修复技术的发展。尽管每种技术都有其自身的局限性和优点，但基质诱导自体软骨细胞植入已被广泛应用并取得了良好的临床效果。我们提出一种以“罗马柱结构”为主要结构，用可吸收钉固定生物膜的技术。所描述的技术能够在确保后续软骨损伤修复顺利进行的同时，实现生物膜的稳定固定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/b94cc43be21d/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/cab1cd9888eb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/39f2c6f8ee00/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/38de1302f4d4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/e6234578ea7b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/36e64988be18/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/d93e7f63f2b7/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/7fd1c545bbfa/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/e1d9b85a3ae9/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/b94cc43be21d/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/cab1cd9888eb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/39f2c6f8ee00/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/38de1302f4d4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/e6234578ea7b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/36e64988be18/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/d93e7f63f2b7/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/7fd1c545bbfa/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/e1d9b85a3ae9/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15f0/11293332/b94cc43be21d/gr9.jpg

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本文引用的文献

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Arthroscopic and open approaches for autologous matrix-induced chondrogenesis repair of the knee have similar results: a meta-analysis.关节镜和开放入路自体基质诱导软骨再生修复膝关节的疗效相似：一项荟萃分析。
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In vitro and in vivo efficacy of naturally derived scaffolds for cartilage repair and regeneration.
天然衍生支架在软骨修复和再生中的体内外疗效。
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Effectiveness of Arthroscopically Assisted Surgery for Ankle Arthrodesis.关节镜辅助下踝关节融合术的疗效
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