Nilsson R, Robertson B
Biol Neonate. 1985;48(6):357-61. doi: 10.1159/000242194.
Premature rabbit neonates were stimulated to breathe for time periods varying between 5 and 150 min. The distribution of bronchiolar epithelial lesions was determined morphometrically. Animals breathing for 5-10 min had no lesions. Focal necrosis and desquamation of bronchiolar epithelium were found in 36 of 46 animals breathing for 15-150 min. These lesions were similar to those previously observed in premature rabbit neonates after a few minutes of artificial ventilation.
对早产兔新生儿进行刺激，使其呼吸5至150分钟不等的时间段。通过形态计量学确定细支气管上皮病变的分布。呼吸5至10分钟的动物没有病变。在呼吸15至150分钟的46只动物中，有36只出现了细支气管上皮的局灶性坏死和脱落。这些病变与之前在早产兔新生儿人工通气几分钟后观察到的病变相似。
