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中国百日咳病例和死亡人数上升:当前趋势和临床解决方案。

Rising pertussis cases and deaths in China: current trends and clinical solutions.

机构信息

Key Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics, Laboratory of Infection and Microbiology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, People's Republic of China.

出版信息

Emerg Microbes Infect. 2024 Dec;13(1):2389086. doi: 10.1080/22221751.2024.2389086. Epub 2024 Aug 21.

Abstract

Pertussis, an acute respiratory infection caused by Bordetella pertussis, has recently experienced a dramatic increase in incidence and associated deaths in China, drawing significant clinical attention. This article retrospectively analyzes national data on pertussis incidence and mortality from 2010 to 2024, exploring potential factors contributing to this trend. It also discusses strategies for enhancing vaccination programs, improving early diagnosis and treatment, and optimizing the clinical management of high-risk infants, with the aim of addressing the challenges posed by the current pertussis epidemic.

摘要

百日咳是由百日咳博德特氏菌引起的急性呼吸道传染病,近期在中国的发病率和相关死亡率急剧上升,引起了临床的高度关注。本文回顾性分析了 2010 年至 2024 年中国百日咳的发病率和死亡率数据,探讨了导致这一趋势的潜在因素。还讨论了加强疫苗接种计划、提高早期诊断和治疗水平以及优化高危婴儿临床管理的策略,旨在应对当前百日咳流行带来的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6193/11340210/8b006d0cc00b/TEMI_A_2389086_F0001_OC.jpg

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