Gebrye T, Akosile C O, Okoye E C, Okoli U V, Fatoye F
Manchester Metropolitan University, Manchester, LAN, UK.
Nnamdi Azikiwe University, Nnewe, Nigeria.
MDM Policy Pract. 2024 Aug 2;9(2):23814683241266193. doi: 10.1177/23814683241266193. eCollection 2024 Jul-Dec.
Stroke and epilepsy are the most common neurologic conditions affecting individuals. The Short Form Six-Dimension Health Index (SF-6D) is a preference-based measure of health developed to estimate utility values from the SF-36. This study estimated utility values for health states of Nigerian individuals with stroke or epilepsy using the SF-36. SF-36 responses from 125 and 69 individuals with stroke and persons with epilepsy, respectively, were transformed into health state utility values using the SF-6D algorithm. The Excel program developed by Brazier and colleagues was used to generate the SF-6D utility score estimated using a set of parametric preference weights. The health state utility values were determined using ordinal health state and standard gamble valuation techniques. Mean () ages of the stroke and epilepsy participants were 63.1 (11) and 39.6 (16) y, respectively. The mean () utility scores for stroke and epilepsy were 0.52 (0.10) and 0.65 (0.1) for standard gamble and 0.48 (0.13) and 0.68 (0.11), respectively, using the ordinal health state paradigm. The mean () utility of stroke (female = 0.46 [0.15]; male = 0.50 [0.12]) and epilepsy (female = 0.65 [0.13], male = 0.69 [0.11]) participants were reported. The mean () annual episodes of seizure was 18.7 (39). To our knowledge, this is the first study to suggest that females with stroke and those with epilepsy considered their health to be poorer than that of their male counterparts. The significance of our findings is that they may be helpful for researchers, policy makers, and clinicians by providing input into economic evaluations to facilitate resource allocation for stroke survivors and people living with epilepsy to improve their health outcomes and reduce the huge burden associated with the conditions.
We estimated a health state utility value for stroke and epilepsy to aid researchers and public health policy makers in conducting health economic analysis and outcomes research.
中风和癫痫是影响个体的最常见神经系统疾病。简式六维健康指数（SF - 6D）是一种基于偏好的健康测量方法，旨在从SF - 36中估计效用值。本研究使用SF - 36估计尼日利亚中风或癫痫患者健康状态的效用值。分别来自125名中风患者和69名癫痫患者的SF - 36回答，使用SF - 6D算法转换为健康状态效用值。由布雷齐尔及其同事开发的Excel程序用于生成使用一组参数偏好权重估计的SF - 6D效用得分。健康状态效用值使用序数健康状态和标准博弈评估技术确定。中风和癫痫参与者的平均（）年龄分别为63.1（11）岁和39.6（16）岁。使用标准博弈时，中风和癫痫的平均（）效用得分分别为0.52（0.10）和0.65（0.1）；使用序数健康状态范式时，分别为0.48（0.13）和0.68（0.11）。报告了中风（女性 = 0.46 [0.15]；男性 = 0.50 [0.12]）和癫痫（女性 = 0.65 [0.13]，男性 = 0.69 [0.11]）参与者的平均（）效用。癫痫发作的平均（）年发作次数为18.7（39）。据我们所知，这是第一项表明中风女性患者和癫痫女性患者认为自己的健康状况比男性患者差的研究。我们研究结果的意义在于，它们可能对研究人员、政策制定者和临床医生有所帮助，为经济评估提供信息，以便为中风幸存者和癫痫患者进行资源分配，改善他们的健康结果，减轻与这些疾病相关的巨大负担。
我们估计了中风和癫痫的健康状态效用值，以帮助研究人员和公共卫生政策制定者进行健康经济分析和结果研究。
