College of Sciences, Northeastern University, Shenyang 110819, PR China.
College of Sciences, Northeastern University, Shenyang 110819, PR China.
Food Chem. 2024 Dec 1;460(Pt 3):140731. doi: 10.1016/j.foodchem.2024.140731. Epub 2024 Aug 2.
17β-E is used in animal growth regulation and agricultural fertilizer, and even ng L mass concentration levels can show biological effects. In this work, Ag NPs was used as surface-enhanced Raman spectroscopy (SERS) source and WS was synthesized by a simple method to provide a uniform distribution platform for Ag NPs. The MIP was the shell, which can selectively enrich the target molecule, pull the distance between the target molecule and SERS source, and protect Ag NPs. A cyclable SERS substrate with high sensitivity for detecting 17β-E in food was constructed. The optimized WS/Ag@MIP as SERS substrate has the advantages of high Enhanced Factor (EF = 2.78 × 10), low detection limit (LOD = 0. 0958 pM), strong anti-interference ability, and good recycling performance. Moreover, the detection of 17β-E in real samples still has good accuracy. This work provides a new possibility for the trace detection of 17β-E in food.
17β-E 用于动物生长调节和农业肥料，即使 ng/L 的质量浓度水平也能表现出生物效应。在这项工作中，Ag NPs 被用作表面增强拉曼光谱（SERS）的源，WS 通过一种简单的方法合成，为 Ag NPs 提供了一个均匀分布的平台。MIP 是外壳，可以选择性地富集目标分子，拉近目标分子与 SERS 源之间的距离，并保护 Ag NPs。构建了一种用于检测食品中 17β-E 的可循环使用的高灵敏度 SERS 基底。优化后的 WS/Ag@MIP 作为 SERS 基底具有高增强因子（EF=2.78×10）、低检测限（LOD=0.0958 pM）、较强的抗干扰能力和良好的循环性能。此外，对实际样品中 17β-E 的检测仍具有良好的准确性。这项工作为食品中痕量 17β-E 的检测提供了新的可能性。
