Eliwa Mohamed S, Al-Essa Laila A, Abou-Senna Amr M, El-Morshedy Mahmoud, El-Sagheer Rashad M
Department of Statistics and Operations Research, College of Science, Qassim University, Saudi Arabia.
Department of Statistics and Computer Science, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.
Heliyon. 2024 Jul 14;10(14):e34418. doi: 10.1016/j.heliyon.2024.e34418. eCollection 2024 Jul 30.
The importance of biomedical physical data is underscored by its crucial role in advancing our comprehension of human health, unraveling the mechanisms underlying diseases, and facilitating the development of innovative medical treatments and interventions. This data serves as a fundamental resource, empowering researchers, healthcare professionals, and scientists to make informed decisions, pioneer research, and ultimately enhance global healthcare quality and individual well-being. It forms a cornerstone in the ongoing pursuit of medical progress and improved healthcare outcomes. This article aims to tackle challenges in estimating unknown parameters and reliability measures related to the modified Weibull distribution when applied to censored progressive biomedical data from the initial failure occurrence. In this context, the article proposes both classical and Bayesian techniques to derive estimates for unknown parameters, survival, and failure rate functions. Bayesian estimates are computed considering both asymmetric and symmetric loss functions. The Markov chain Monte Carlo method is employed to obtain these Bayesian estimates and their corresponding highest posterior density credible intervals. Due to the inherent complexity of these estimators, which cannot be theoretically compared, a simulation study is conducted to evaluate the performance of various estimation procedures. Additionally, a range of optimization criteria is utilized to identify the most effective progressive control strategies. Lastly, the article presents a medical application to illustrate the effectiveness of the proposed estimators. Numerical findings indicate that Bayesian estimates outperform other estimation methods by achieving minimal root mean square errors and narrower interval lengths.
生物医学物理数据的重要性体现在其在促进我们对人类健康的理解、揭示疾病潜在机制以及推动创新医疗治疗和干预措施发展方面的关键作用。这些数据是一种基础资源,使研究人员、医疗保健专业人员和科学家能够做出明智决策、开展前沿研究,并最终提高全球医疗质量和个人福祉。它是持续追求医学进步和改善医疗结果的基石。本文旨在解决在将修正威布尔分布应用于从初始故障发生起的删失渐进生物医学数据时,估计未知参数和可靠性度量方面的挑战。在此背景下,本文提出了经典和贝叶斯技术来推导未知参数、生存函数和失效率函数的估计值。考虑非对称和对称损失函数来计算贝叶斯估计值。采用马尔可夫链蒙特卡罗方法来获得这些贝叶斯估计值及其相应的最高后验密度可信区间。由于这些估计量具有内在复杂性,无法从理论上进行比较,因此进行了一项模拟研究来评估各种估计程序的性能。此外,利用一系列优化标准来确定最有效的渐进控制策略。最后,本文给出了一个医学应用实例来说明所提出估计量的有效性。数值结果表明,贝叶斯估计值通过实现最小均方误差和更窄的区间长度,优于其他估计方法。