From Agriculture to Clinics: Unlocking the Potential of Magnetized Water for Planetary and Human Health.

Magnetized water (MW) is a form of liquid water that has been exposed to a magnetic field to alter its hydrogen bonding structure, resulting in the formation of water molecule clusters of various sizes and configurations connected by hydrogen bonds. This magnetization process induces several changes in the physicochemical properties of water, such as increased pH, electrical conductivity, and dissolved oxygen content, as well as decreased surface tension, density, and evaporation temperature compared to untreated water. In this narrative review, we explore the effective utilization of MW in agriculture, where it has a well-established history of applications, and its potential for direct applications in the medical field, which are currently at the forefront of research. MW is one of the most promising innovations for facilitating the transition from unsustainable to sustainable agriculture, which is expected to yield positive human health outcomes by promoting the consumption of less processed foods and reducing resource consumption. In addition to these indirect effects on human health, preclinical research utilizing animal models has demonstrated that water magnetization exerts beneficial effects on diabetes, renal function, bone health, and fertility. These health benefits appear to stem from the ability of MW to increase the activity of antioxidant enzymes while decreasing lipid peroxidation and inflammatory markers. In terms of direct human applications, MW has been primarily studied in the fields of dentistry and dermatology. MW mouthrinse has consistently shown efficacy against , with studies reporting comparable effects to chlorhexidine. In dermatology, the topical application of MW has demonstrated improvements in skin biophysical parameters, increased hair count and hair mass index, and promoted the healing of challenging wounds. Intriguingly, these effects on human skin seem to be mediated by local activation of autophagy, potentially through mild alkaline stress. In conclusion, this review underscores the promising role of MW in promoting a holistic approach to planetary and human health. Future studies should focus on standardizing the magnetization process, exploring the molecular mechanisms underlying MW-induced autophagy, and investigating the potential of MW as a complementary strategy for treating human diseases characterized by impaired autophagy.