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乳腺癌患者的类肉瘤样反应:两例报告

Sarcoid-Like Reactions in Breast Cancer Patients: A Report of Two Cases.

作者信息

Marinos Nikolaos, Visvikis Michail, Georgakopoulou Vasiliki E, Drakopanagiotakis Fotios, Steiropoulos Paschalis

机构信息

Department of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GRC.

Department of Pathophysiology/Pulmonologist, Laiko General Hospital, Athens, GRC.

出版信息

Cureus. 2024 Jul 8;16(7):e64096. doi: 10.7759/cureus.64096. eCollection 2024 Jul.

DOI:10.7759/cureus.64096
PMID:39114256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11305606/
Abstract

Sarcoid-like reactions (SLR) in patients with malignancies are a relatively common finding. Defined by the presence of non-caseating granulomas, SLR does not meet the clinical criteria for classic sarcoidosis. In cancer patients, SLR often presents a challenging differential diagnosis, as it must be distinguished from disease progression due to malignancy. We present two cases of SLRs associated with breast cancer, underscoring the need for heightened vigilance among physicians. SLR should always be considered a potential diagnosis in these patients, with histological confirmation being essential for accurate identification.

摘要

恶性肿瘤患者中的结节病样反应(SLR)是一种相对常见的表现。SLR由非干酪样肉芽肿的存在所定义,不符合经典结节病的临床标准。在癌症患者中,SLR常常带来具有挑战性的鉴别诊断,因为它必须与恶性肿瘤导致的疾病进展相区分。我们呈现两例与乳腺癌相关的SLR病例,强调医生需要提高警惕。在这些患者中,SLR应始终被视为一种潜在的诊断,组织学确认对于准确识别至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1259/11305606/541fc590c361/cureus-0016-00000064096-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1259/11305606/5227dd7dea0b/cureus-0016-00000064096-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1259/11305606/541fc590c361/cureus-0016-00000064096-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1259/11305606/5227dd7dea0b/cureus-0016-00000064096-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1259/11305606/541fc590c361/cureus-0016-00000064096-i02.jpg

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2
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Front Med (Lausanne). 2022 Aug 17;9:884386. doi: 10.3389/fmed.2022.884386. eCollection 2022.
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Clinical Features, Histopathology and Differential Diagnosis of Sarcoidosis.
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Cells. 2021 Dec 26;11(1):59. doi: 10.3390/cells11010059.
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Pulmonary adverse events due to immune checkpoint inhibitors: A literature review.免疫检查点抑制剂所致肺部不良事件:文献综述
Monaldi Arch Chest Dis. 2021 Oct 11;92(2). doi: 10.4081/monaldi.2021.2008.
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Int J Surg Case Rep. 2021 Aug;85:106280. doi: 10.1016/j.ijscr.2021.106280. Epub 2021 Aug 4.
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