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微生物群:整合医学的基础。

The Microbiome: A Foundation for Integrative Medicine.

作者信息

Manske Shawn

机构信息

Assistant Director of Clinical Education, Biocidin Botanicals, Watsonville CA, USA.

出版信息

Integr Med (Encinitas). 2024 Jul;23(3):28-31.

PMID:39114281
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11302976/
Abstract

CONTEXT

No organ system better integrates interconnectivity across specialties and disciplines than the microbiome. Scientific focus is shifting from microbes as harbingers of disease toward microbes as symbiotic, balanced, commensal ecologies.

OBJECTIVE

The study intended to discuss and examine the human microbiome, including its development in early life; its impact on various physiological processes that occur throughout the body; and its relationship to dysbiosis; and to investigate microbial mechanisms with clinical applicability across medical specialties.

SETTING

The study took place at Biocidin Botanicals in Watsonville CA, USA.

RESULTS

Accumulating research upholds the human microbiome as both a predictive biomarker for disease risk and a viable treatment option for modulating the course of illness. Prebiotic and probiotic interventions continue to demonstrate clinical utility, particularly for gastrointestinal, dermatological, inflammatory, metabolic, and mental-health disorders.

CONCLUSIONS

Just as germ theory revolutionized infection control in the twentieth century, microbiome systems science stands to transform the conceptualization of health as the balanced coexistence of human and microbial cells in the twenty-first century.

摘要

背景

没有哪个器官系统能比微生物群更好地整合各专业和学科之间的相互联系。科学关注点正从将微生物视为疾病的先兆,转向将其视为共生、平衡的共栖生态。

目的

该研究旨在讨论和审视人类微生物群,包括其在生命早期的发育情况;其对全身发生的各种生理过程的影响;及其与生态失调的关系;并研究具有跨医学专业临床适用性的微生物机制。

地点

该研究在美国加利福尼亚州沃森维尔的Biocidin Botanicals公司进行。

结果

越来越多的研究支持将人类微生物群既作为疾病风险的预测生物标志物,又作为调节疾病进程的可行治疗选择。益生元和益生菌干预措施继续显示出临床效用,特别是对胃肠道、皮肤病、炎症、代谢和心理健康障碍。

结论

正如病菌学说在20世纪彻底改变了感染控制一样,微生物群系统科学有望在21世纪改变健康的概念,即人类和微生物细胞平衡共存。