急性心力衰竭患者的心力衰竭专科护理与长期预后
Heart Failure Specialist Care and Long-Term Outcomes for Patients Admitted With Acute Heart Failure.
作者信息
Cannata Antonio, Mizani Mehrdad A, Bromage Daniel I, Piper Susan E, Hardman Suzanna M C, Sudlow Cathie, de Belder Mark, Scott Paul A, Deanfield John, Gardner Roy S, Clark Andrew L, Cleland John G F, McDonagh Theresa A
机构信息
British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine, Faculty of Life Science, King's College London, London, United Kingdom; Cardiology Department, King's College Hospital NHS Foundation Trust, London, United Kingdom.
British Heart Foundation Data Science Centre, Health Data Research United Kingdom, London, United Kingdom.
出版信息
JACC Heart Fail. 2025 Mar;13(3):402-413. doi: 10.1016/j.jchf.2024.06.013. Epub 2024 Aug 7.
BACKGROUND
For patients with acute heart failure (HF), specialist HF care during admission improves diagnosis and treatments.
OBJECTIVES
The authors aimed to investigate the association of HF specialist care with in-hospital and longer term prognosis.
METHODS
The authors used data from the National Heart Failure Audit from January 1, 2018, to December 31, 2022, linked to electronic records for hospitalization and deaths. All-cause mortality was the primary outcome measure and in-hospital mortality the secondary outcome measure.
RESULTS
Data for 227,170 patients admitted to hospital with HF (median age: 81 years; IQR: 72-88 years), were analyzed. Approximately 80% of acute HF admissions received support from HF specialists. Thirty-nine percent of patients (n = 70,720) were seen by a multidisciplinary team (HF physicians and heart failure specialist nurses [HFSNs]), 22% (n = 40,330) were seen by HFSNs alone, and the remaining 39% (n = 71,700) were seen exclusively by specialist HF physicians. At discharge, more patients who received HF specialist care were prescribed medical therapy for HF and had specialized follow-up. Conversely, diuretic agents were prescribed to fewer patients. HF specialist care was independently associated with a higher rate of prescribing HF therapies at discharge and a lower likelihood of receiving diuretic therapy (OR: 0.90 [95% CI: 0.86-0.95]; P < 0.001). HF specialist care was associated with better long-term survival (HR: 0.89 [95% CI: 0.87-0.90]; P < 0.001) and lower in-hospital mortality (OR: 0.92 [95% CI: 0.0.88-0.97]; P < 0.001).
CONCLUSIONS
Receiving HF specialist care during admission for HF is associated with a higher rate of implementation of medical therapy, fewer discharges on diuretic therapy, and lower in-hospital and long-term mortality across the left ventricular ejection fraction spectrum, especially for patients with heart failure with reduced ejection fraction.
背景
对于急性心力衰竭(HF)患者,住院期间接受专科HF护理可改善诊断和治疗。
目的
作者旨在研究HF专科护理与住院及长期预后之间的关联。
方法
作者使用了2018年1月1日至2022年12月31日国家心力衰竭审计的数据,并与住院和死亡的电子记录相链接。全因死亡率是主要结局指标,住院死亡率是次要结局指标。
结果
分析了227,170例因HF住院患者的数据(中位年龄:81岁;四分位间距:72 - 88岁)。约80%的急性HF住院患者接受了HF专科医生的支持。39%的患者(n = 70,720)由多学科团队(HF内科医生和心力衰竭专科护士[HFSNs])诊治,22%(n = 40,330)仅由HFSNs诊治,其余39%(n = 71,700)仅由HF专科内科医生诊治。出院时,接受HF专科护理的患者中,更多患者接受了HF药物治疗并进行了专科随访。相反,使用利尿剂的患者较少。HF专科护理与出院时开具HF治疗药物的比例较高以及接受利尿剂治疗的可能性较低独立相关(比值比:0.90 [95%置信区间:0.86 - 0.95];P < 0.001)。HF专科护理与更好的长期生存率(风险比:0.89 [95%置信区间:0.87 - 0.90];P < 0.001)和较低的住院死亡率(比值比:0.92 [95%置信区间:(0.88 - 0.97];P < 0.001)相关。
结论
HF住院期间接受专科护理与药物治疗的实施率较高、利尿剂治疗出院人数较少以及整个左心室射血分数范围内较低住院和长期死亡率相关,尤其是射血分数降低的心力衰竭患者。