Glad'ko I A, Korshunov V M, Pinegin B V
Zh Mikrobiol Epidemiol Immunobiol. 1985 Feb(2):54-7.
Human immunoglobulins, injected into mice subcutaneously after their irradiation or at the beginning of antibiotic therapy, protected the mucous membrane of the proximal section of the small intestine from the penetration of enterobacteria. The formation of the protective barrier was observed when immunoglobulin preparations with the titer of antibodies to Escherichia coli O14 between 1:16 and 1:256 was used. The preliminary exhaustion of immunoglobulin preparations with E. coli strain O14 led to the complete loss of their protective properties.
在小鼠接受辐照后或在抗生素治疗开始时皮下注射人免疫球蛋白，可保护小肠近端黏膜免受肠杆菌的侵入。当使用抗大肠杆菌O14抗体效价在1:16至1:256之间的免疫球蛋白制剂时，可观察到保护屏障的形成。用大肠杆菌O14菌株预先耗尽免疫球蛋白制剂会导致其保护特性完全丧失。
