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LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.

作者信息

Goldsmith Moshe, Avram Liat, Brandis Alexander, Mehlman Tevie, Ben-Dor Shifra, Peleg Yoav, Ben-Zeev Efrat, Barbole Ranjit S, Reich Ziv

机构信息

Dept. of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel.

Dept. of Chemical Research Support, Weizmann Institute of Science, Rehovot, 7610001, Israel.

出版信息

Nat Commun. 2024 Aug 8;15(1):6715. doi: 10.1038/s41467-024-50703-4.

DOI:10.1038/s41467-024-50703-4
PMID:39117614
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11310188/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ba/11310188/163c9adbbde9/41467_2024_50703_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ba/11310188/f64bb41ea0a4/41467_2024_50703_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ba/11310188/163c9adbbde9/41467_2024_50703_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ba/11310188/f64bb41ea0a4/41467_2024_50703_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ba/11310188/163c9adbbde9/41467_2024_50703_Fig2_HTML.jpg

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LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.LsBOS利用由LsAAE3产生的草酰辅酶A在草豌豆中合成β-ODAP。
Nat Commun. 2024 Aug 8;15(1):6715. doi: 10.1038/s41467-024-50703-4.
2
Reply to: LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.回复：在草豌豆中，LsBOS利用LsAAE3产生的草酰辅酶A来合成β-草酰氨基丙氨酸。
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本文引用的文献

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Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus.基因组学和生化分析揭示了在豌豆中β-L-ODAP 生物合成的关键代谢物。
Nat Commun. 2023 Feb 16;14(1):876. doi: 10.1038/s41467-023-36503-2.
2
The identification and characterization of an oxalyl-CoA synthetase from grass pea ( L.).来自草豌豆（L.）的草酰辅酶A合成酶的鉴定与特性分析。
RSC Chem Biol. 2022 Feb 8;3(3):320-333. doi: 10.1039/d1cb00202c. eCollection 2022 Mar 9.
3
Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.
鉴定和表征在羽扇豆生物合成神经毒素β-ODAP 中的关键酶。
J Biol Chem. 2022 May;298(5):101806. doi: 10.1016/j.jbc.2022.101806. Epub 2022 Mar 7.
4
Wild Soybean Oxalyl-CoA Synthetase Degrades Oxalate and Affects the Tolerance to Cadmium and Aluminum Stresses.野生大豆草酰辅酶 A 合成酶降解草酸盐并影响对镉和铝胁迫的耐受性。
Int J Mol Sci. 2020 Nov 23;21(22):8869. doi: 10.3390/ijms21228869.
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PLoS One. 2016 Feb 22;11(2):e0149850. doi: 10.1371/journal.pone.0149850. eCollection 2016.
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