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Reply to: LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.

作者信息

Edwards Anne, Jiang Zhouqian, Nepogodiev Sergey, Rejzek Martin, Martin Cathie, Emmrich Peter M F

机构信息

John Innes Centre, Norwich Research Park, Colney Lane, Norwich, NR4 7UH, UK.

Norwich Institute for Sustainable Development, School of Global Development, University of East Anglia, Norwich, NR4 7TJ, UK.

出版信息

Nat Commun. 2024 Aug 8;15(1):6714. doi: 10.1038/s41467-024-50705-2.

DOI:10.1038/s41467-024-50705-2
PMID:39117668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11310462/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0118/11310462/74fbffc9cc65/41467_2024_50705_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0118/11310462/92683b29ce7b/41467_2024_50705_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0118/11310462/487363cc1681/41467_2024_50705_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0118/11310462/74fbffc9cc65/41467_2024_50705_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0118/11310462/92683b29ce7b/41467_2024_50705_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0118/11310462/487363cc1681/41467_2024_50705_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0118/11310462/74fbffc9cc65/41467_2024_50705_Fig3_HTML.jpg

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Reply to: LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.回复：在草豌豆中，LsBOS利用LsAAE3产生的草酰辅酶A来合成β-草酰氨基丙氨酸。
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本文引用的文献

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Diamine Oxidase as a Therapeutic Enzyme: Study of Germination from Vegetal Sources and Investigation of the Presence of β-N-Oxalyl-L-α,β-diaminopropionic Acid (β-ODAP) Using LC-MS/MS.二胺氧化酶作为一种治疗酶：从植物来源研究发芽，并使用 LC-MS/MS 研究 β-N-草酰基-L-α,β-二氨基丙酸（β-ODAP）的存在。
Int J Mol Sci. 2023 Feb 27;24(5):4625. doi: 10.3390/ijms24054625.
2
Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus.基因组学和生化分析揭示了在豌豆中β-L-ODAP 生物合成的关键代谢物。
Nat Commun. 2023 Feb 16;14(1):876. doi: 10.1038/s41467-023-36503-2.
3
The identification and characterization of an oxalyl-CoA synthetase from grass pea ( L.).
来自草豌豆（L.）的草酰辅酶A合成酶的鉴定与特性分析。
RSC Chem Biol. 2022 Feb 8;3(3):320-333. doi: 10.1039/d1cb00202c. eCollection 2022 Mar 9.
4
Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.鉴定和表征在羽扇豆生物合成神经毒素β-ODAP 中的关键酶。
J Biol Chem. 2022 May;298(5):101806. doi: 10.1016/j.jbc.2022.101806. Epub 2022 Mar 7.
5
Regulation of coenzyme A levels by degradation: the 'Ins and Outs'.辅酶 A 水平的降解调控：“内与外”。
Prog Lipid Res. 2020 Apr;78:101028. doi: 10.1016/j.plipres.2020.101028. Epub 2020 Mar 29.
6
Coenzyme A and its derivatives: renaissance of a textbook classic.辅酶A及其衍生物：教科书经典的复兴
Biochem Soc Trans. 2014 Aug;42(4):1025-32. doi: 10.1042/BST20140176.
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Prog Lipid Res. 2005 Mar-May;44(2-3):125-53. doi: 10.1016/j.plipres.2005.04.001. Epub 2005 Apr 20.
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Chemical synthesis of oxalyl-coenzyme A and its enzymic reduction to glyxylate.草酰辅酶A的化学合成及其酶促还原为乙醛酸。
Biochim Biophys Acta. 1962 Feb 26;57:398-400. doi: 10.1016/0006-3002(62)91142-3.
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Coenzyme A and carnitine distribution in normal and ischemic hearts.
J Biol Chem. 1978 Jun 25;253(12):4310-8.