回复：在草豌豆中，LsBOS利用LsAAE3产生的草酰辅酶A来合成β-草酰氨基丙氨酸。 - Suppr

Reply to: LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.

作者信息

Edwards Anne, Jiang Zhouqian, Nepogodiev Sergey, Rejzek Martin, Martin Cathie, Emmrich Peter M F

机构信息

John Innes Centre, Norwich Research Park, Colney Lane, Norwich, NR4 7UH, UK.

Norwich Institute for Sustainable Development, School of Global Development, University of East Anglia, Norwich, NR4 7TJ, UK.

出版信息

Nat Commun. 2024 Aug 8;15(1):6714. doi: 10.1038/s41467-024-50705-2.

DOI:10.1038/s41467-024-50705-2

PMID:39117668

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11310462/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0118/11310462/92683b29ce7b/41467_2024_50705_Fig1_HTML.jpg

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Reply to: LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.回复：在草豌豆中，LsBOS利用LsAAE3产生的草酰辅酶A来合成β-草酰氨基丙氨酸。

Nat Commun. 2024 Aug 8;15(1):6714. doi: 10.1038/s41467-024-50705-2.

LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.LsBOS利用由LsAAE3产生的草酰辅酶A在草豌豆中合成β-ODAP。

Nat Commun. 2024 Aug 8;15(1):6715. doi: 10.1038/s41467-024-50703-4.

Role of abscisic acid in modulating drought acclimation, agronomic characteristics and β-N-oxalyl-L-α,β-diaminopropionic acid (β-ODAP) accumulation in grass pea (Lathyrus sativus L.).脱落酸在调节鹰嘴豆（草香豌豆，Lathyrus sativus L.）干旱适应性、农艺性状及β-N-草酰-L-α,β-二氨基丙酸（β-ODAP）积累中的作用

J Sci Food Agric. 2022 Apr;102(6):2553-2562. doi: 10.1002/jsfa.11597. Epub 2021 Nov 2.

Neurotoxin (N-Oxalyl-L-α,β-Diamino Propionic Acid) Content in Different Plant Parts of Grass Pea ( L.) Spanning Seedling to Maturity Stage: Does It Increase over Time?不同生长阶段草木樨（L.）中神经毒素（N-草酰-L-α,β-二氨基丙酸）含量：是否随时间推移而增加？

Molecules. 2022 Jun 8;27(12):3683. doi: 10.3390/molecules27123683.

Hydroxyl radical scavenging activity of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid.

Phytochemistry. 2001 Nov;58(5):759-62. doi: 10.1016/s0031-9422(01)00250-3.

A novel lipid transfer protein from the pea Pisum sativum: isolation, recombinant expression, solution structure, antifungal activity, lipid binding, and allergenic properties.一种来自豌豆（Pisum sativum）的新型脂质转移蛋白：分离、重组表达、溶液结构、抗真菌活性、脂质结合及致敏特性

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Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus.基因组学和生化分析揭示了在豌豆中β-L-ODAP 生物合成的关键代谢物。

Nat Commun. 2023 Feb 16;14(1):876. doi: 10.1038/s41467-023-36503-2.

The identification and characterization of an oxalyl-CoA synthetase from grass pea ( L.).来自草豌豆（L.）的草酰辅酶A合成酶的鉴定与特性分析。

RSC Chem Biol. 2022 Feb 8;3(3):320-333. doi: 10.1039/d1cb00202c. eCollection 2022 Mar 9.

β-Amyrin Synthase1 Controls the Accumulation of the Major Saponins Present in Pea (Pisum sativum).β-香树脂醇合酶 1 控制豌豆（Pisum sativum）中主要皂苷的积累。

Plant Cell Physiol. 2021 Oct 1;62(5):784-797. doi: 10.1093/pcp/pcab049.

Evidence of non-functional redundancy between two pea h-type thioredoxins by specificity and stability studies.通过特异性和稳定性研究证明两个豌豆 h 型硫氧还蛋白之间不存在功能冗余。

J Plant Physiol. 2010 Apr 15;167(6):423-9. doi: 10.1016/j.jplph.2009.10.017. Epub 2009 Dec 14.

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Diamine Oxidase as a Therapeutic Enzyme: Study of Germination from Vegetal Sources and Investigation of the Presence of β-N-Oxalyl-L-α,β-diaminopropionic Acid (β-ODAP) Using LC-MS/MS.二胺氧化酶作为一种治疗酶：从植物来源研究发芽，并使用 LC-MS/MS 研究 β-N-草酰基-L-α,β-二氨基丙酸（β-ODAP）的存在。

Int J Mol Sci. 2023 Feb 27;24(5):4625. doi: 10.3390/ijms24054625.

Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus.基因组学和生化分析揭示了在豌豆中β-L-ODAP 生物合成的关键代谢物。

Nat Commun. 2023 Feb 16;14(1):876. doi: 10.1038/s41467-023-36503-2.

The identification and characterization of an oxalyl-CoA synthetase from grass pea ( L.).来自草豌豆（L.）的草酰辅酶A合成酶的鉴定与特性分析。

RSC Chem Biol. 2022 Feb 8;3(3):320-333. doi: 10.1039/d1cb00202c. eCollection 2022 Mar 9.

Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.鉴定和表征在羽扇豆生物合成神经毒素β-ODAP 中的关键酶。

J Biol Chem. 2022 May;298(5):101806. doi: 10.1016/j.jbc.2022.101806. Epub 2022 Mar 7.

Regulation of coenzyme A levels by degradation: the 'Ins and Outs'.辅酶 A 水平的降解调控：“内与外”。

Prog Lipid Res. 2020 Apr;78:101028. doi: 10.1016/j.plipres.2020.101028. Epub 2020 Mar 29.

Coenzyme A and its derivatives: renaissance of a textbook classic.辅酶A及其衍生物：教科书经典的复兴

Biochem Soc Trans. 2014 Aug;42(4):1025-32. doi: 10.1042/BST20140176.

Contribution of CoA ligases to benzenoid biosynthesis in petunia flowers.CoA 连接酶在矮牵牛花朵苯丙烷类生物合成中的作用。

Plant Cell. 2012 May;24(5):2015-30. doi: 10.1105/tpc.112.097519. Epub 2012 May 30.

Coenzyme A: back in action.辅酶A：恢复作用。

Prog Lipid Res. 2005 Mar-May;44(2-3):125-53. doi: 10.1016/j.plipres.2005.04.001. Epub 2005 Apr 20.

Chemical synthesis of oxalyl-coenzyme A and its enzymic reduction to glyxylate.草酰辅酶A的化学合成及其酶促还原为乙醛酸。

Biochim Biophys Acta. 1962 Feb 26;57:398-400. doi: 10.1016/0006-3002(62)91142-3.

Coenzyme A and carnitine distribution in normal and ischemic hearts.

J Biol Chem. 1978 Jun 25;253(12):4310-8.

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Reply to: LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.

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