Helmbold W, Prokop O, Uhlenbruck G, Böhmer G, Lütticken R
Biomed Biochim Acta. 1985;44(11-12):K91-6.
A new group of vertebrate lectins has been discovered in snake venom preparations. These lectins are cell agglutinating, but not glycoconjugate precipitating. The specificity is directed towards receptors with terminal D-galactose, beta-linked. From the crude preparations strong T- and potent B-cell mitogens can be obtained by fractionation. The T-cell mitogenic lectin could be characterized as an anti-galactan, which reacts with group B streptococci of type II, and with the other types only after neuraminidase treatment. For comparison, other lectins have been tested with group B streptococci, too.
在蛇毒制剂中发现了一组新的脊椎动物凝集素。这些凝集素可使细胞凝集，但不能使糖缀合物沉淀。其特异性针对具有β-连接的末端D-半乳糖的受体。通过分级分离可从粗制制剂中获得强T细胞和强效B细胞有丝分裂原。T细胞有丝分裂凝集素可被鉴定为抗半乳聚糖，它与II型B组链球菌反应，而其他类型的B组链球菌只有在经神经氨酸酶处理后才会与之反应。为作比较，也用B组链球菌对其他凝集素进行了测试。
