King Alexis C, Villalobos Cynthia, Vosti Paul, Jensen Courtney D
Department of Health and Exercise Sciences, University of the Pacific, Stockton, CA 95211, USA.
St. Joseph's Medical Center, Stockton, CA 95204, USA.
Healthcare (Basel). 2024 Aug 1;12(15):1528. doi: 10.3390/healthcare12151528.
Type 2 diabetes mellitus (T2DM) affects one in ten individuals in the United States, with rates expected to rise significantly. This novel study aimed to evaluate the impact of a structured exercise program on glycated hemoglobin (HbA1c) levels among males and females with T2DM, and to compare the effects of different volumes of combined aerobic and resistance exercise. A total of 67 adult participants with T2DM were randomly assigned to two groups: Group 1 (exercise classes and walking sessions) and Group 2 (exercise classes only). After 10 weeks, 39 participants completed the intervention and 34 had complete HbA1c records. Results indicated a significant improvement in HbA1c levels overall, with males exhibiting a greater decrease compared to females. Minimal baseline differences were observed between the walking and non-walking groups and improvements in HbA1c were noted in both groups with no significant differences. These findings suggested potential sex-specific differences in response to structured exercise programs. The study highlighted the importance of tailored exercise interventions in healthcare while managing T2DM. Further research is necessary to optimize exercise prescriptions and evaluate long-term benefits, but the current evidence supports structured exercise as a valuable component of comprehensive diabetes care. This research underscores the need for personalized approaches in exercise regimens, contributing to the growing body of knowledge on sex-specific responses to T2DM interventions.
2型糖尿病（T2DM）在美国每十人中就有一人受其影响，且发病率预计将大幅上升。这项新研究旨在评估结构化运动计划对患有T2DM的男性和女性糖化血红蛋白（HbA1c）水平的影响，并比较不同运动量的有氧和抗阻运动组合的效果。共有67名患有T2DM的成年参与者被随机分为两组：第1组（运动课程和步行训练）和第2组（仅运动课程）。10周后，39名参与者完成了干预，34名有完整的HbA1c记录。结果表明，总体HbA1c水平有显著改善，男性的下降幅度大于女性。步行组和非步行组之间观察到的基线差异极小，两组的HbA1c均有改善，且无显著差异。这些发现表明，在对结构化运动计划的反应中可能存在性别差异。该研究强调了在管理T2DM的医疗保健中进行量身定制的运动干预的重要性。有必要进行进一步研究以优化运动处方并评估长期益处，但目前的证据支持结构化运动作为综合糖尿病护理的重要组成部分。这项研究强调了运动方案中个性化方法的必要性，为关于对T2DM干预的性别特异性反应的知识体系增添了内容。
