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有氧运动作为一种非药物干预手段,用于改善2型糖尿病患者的代谢和血流动力学指标。

Aerobic exercise as a non-pharmacological intervention for improving metabolic and hemodynamic profiles in type 2 diabetes.

作者信息

Almutairi Aeshah Hamdan, Almutairi Nayef Shabbab, Mousa Nasser, Elsayed Ashraf, El-Sehrawy Amr, Elmetwalli Alaa

机构信息

Public Health Department, Health Sciences College at Al Leith, Umm Al Qura University, 24382, Mecca, Saudi Arabia.

Tropical Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

出版信息

Ir J Med Sci. 2024 Dec;193(6):2781-2790. doi: 10.1007/s11845-024-03783-6. Epub 2024 Aug 19.

DOI:10.1007/s11845-024-03783-6
PMID:39158674
Abstract

BACKGROUND

Type 2 Diabetes Mellitus (T2DM) is a global health concern associated with numerous complications. Aerobic exercise is recognized as a crucial non-pharmacological intervention for T2DM management, but its specific effects on key health parameters warrant further investigation.

OBJECTIVE

This study aimed to evaluate the impact of a structured 8-week aerobic exercise program on fasting blood glucose (FBG), glycated haemoglobin (HbA1c), body mass index (BMI), blood pressure (BP), and resting heart rate (RHR) in individuals with T2DM.

METHODS

A prospective study was conducted with 100 participants diagnosed with T2DM. The intervention group (n = 50) underwent a supervised aerobic exercise program for eight weeks, while the control group (n = 50) received no structured exercise intervention. Pre- and post-intervention assessments were conducted to measure FBG, HbA1c, BMI, BP, RHR, and VO₂ max were taken.

RESULTS

The aerobic group exhibited a significant reduction in FBG, declining from 141 to 132 mg/dl. Correspondingly, HbA1c decreased from 7.93 to 7.15%. Additionally, the aerobic group demonstrated a notable decrease in RHR from 72 to 66 bpm, indicating improved cardiovascular fitness. Concurrently, VO2 max increased from 22 to 26 mL/kg/min, further supporting the enhancement of cardiorespiratory capacity. Trends toward improvement were also observed in SBP and DBP. Correlation analysis revealed significant relationships between various health parameters, highlighting the interconnectedness of these variables in T2DM management.

CONCLUSIONS

This study provides robust evidence supporting the benefits of aerobic exercise in individuals with T2DM. The improvements in glycemic control, blood pressure, and cardiorespiratory fitness underscore the importance of incorporating structured exercise programs into diabetes management protocols. The results emphasize the importance of incorporating regular physical activity into diabetes management strategies to optimize health outcomes and reduce the risk of complications.

摘要

背景

2型糖尿病(T2DM)是一个全球性的健康问题,与多种并发症相关。有氧运动被认为是T2DM管理的关键非药物干预措施,但其对关键健康参数的具体影响值得进一步研究。

目的

本研究旨在评估为期8周的结构化有氧运动计划对T2DM患者空腹血糖(FBG)、糖化血红蛋白(HbA1c)、体重指数(BMI)、血压(BP)和静息心率(RHR)的影响。

方法

对100名被诊断为T2DM的参与者进行了一项前瞻性研究。干预组(n = 50)进行了为期八周的有监督的有氧运动计划,而对照组(n = 50)没有接受结构化运动干预。在干预前后进行评估,以测量FBG、HbA1c、BMI、BP、RHR,并测量最大摄氧量(VO₂ max)。

结果

有氧运动组的FBG显著降低,从141降至132mg/dl。相应地,HbA1c从7.93%降至7.15%。此外,有氧运动组的RHR从72次/分钟显著降至66次/分钟,表明心血管健康状况有所改善。同时,VO2 max从22增加到26 mL/kg/min,进一步支持心肺功能的增强。收缩压(SBP)和舒张压(DBP)也有改善趋势。相关性分析揭示了各种健康参数之间的显著关系,突出了这些变量在T2DM管理中的相互关联性。

结论

本研究提供了有力证据,支持有氧运动对T2DM患者有益。血糖控制、血压和心肺健康的改善强调了将结构化运动计划纳入糖尿病管理方案的重要性。结果强调了将定期体育活动纳入糖尿病管理策略以优化健康结果和降低并发症风险的重要性。

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