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基于双金属等离子体层和黑磷的纳米传感器：在尿液葡萄糖检测中的应用。

Nanosensors Based on Bimetallic Plasmonic Layer and Black Phosphorus: Application to Urine Glucose Detection.

机构信息

Laboratory of Advanced Materials Studies and Applications (LEM2A), Physics Department, Faculty of Science, Moulay Ismail University of Meknes, B.P. 11201 Zitoune Meknès, Morocco.

Faculty of Medicine and Pharmacy of Beni Mellal, Sultane Moulay Slimane University, M'ghila Campus, 23030 Beni Mellal, Morocco.

出版信息

Sensors (Basel). 2024 Aug 5;24(15):5058. doi: 10.3390/s24155058.

DOI:10.3390/s24155058
PMID:39124105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11315007/
Abstract

This paper presents a new biosensor design based on the Kretschmann configuration, for the detection of analytes at different refractive indices. Our studied design consists of a TiO/SiO bi-layer sandwiched between a BK7 prism and a bimetallic layer of Ag/Au plasmonic materials, covered by a layer of black phosphorus placed below the analyte-containing detection medium. The different layers of our structure and analyte detection were optimized using the angular interrogation method. High performance was achieved, with a sensitivity of 240 deg/RIU and a quality factor of 34.7 RIU. This biosensor can detect analytes with a wide refractive index range between 1.330 and 1.347, such as glucose detection in urine samples using a refractive index variation of 10-3. This capability offers a wide range of applications for biomedical and biochemical detection and selectivity.

摘要

本文提出了一种基于 Kretschmann 配置的新型生物传感器设计，用于检测不同折射率下的分析物。我们的研究设计由 TiO/SiO 双层夹在 BK7 棱镜和银/金等离子体材料的双金属层之间组成，在含有分析物的检测介质下方覆盖一层黑磷。使用角度询问方法优化了我们结构和分析物检测的不同层。实现了高性能，灵敏度为 240 deg/RIU，品质因数为 34.7 RIU。该生物传感器可以检测折射率范围在 1.330 到 1.347 之间的分析物，例如使用折射率变化为 10-3 的尿液样本中的葡萄糖检测。这种能力为生物医学和生化检测提供了广泛的应用和选择性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/0d7d3c90eca7/sensors-24-05058-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/5a6805fb25d7/sensors-24-05058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/e167e4ccb5d2/sensors-24-05058-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/7266662672f4/sensors-24-05058-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/8c1f7784c9ae/sensors-24-05058-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/cdd29f8dd972/sensors-24-05058-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/9f5b7689162a/sensors-24-05058-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/0d7d3c90eca7/sensors-24-05058-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/5a6805fb25d7/sensors-24-05058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/e167e4ccb5d2/sensors-24-05058-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/7266662672f4/sensors-24-05058-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/8c1f7784c9ae/sensors-24-05058-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/cdd29f8dd972/sensors-24-05058-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/9f5b7689162a/sensors-24-05058-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5943/11315007/0d7d3c90eca7/sensors-24-05058-g007.jpg

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