Nešić Milica D, Nešić Milan S, Dimitrijević Milan Ž, Radulović Niko S
Department of Chemistry, Faculty of Sciences and Mathematics, University of Niš, Višegradska 33, 18000 Niš, Serbia.
Plants (Basel). 2024 Jul 26;13(15):2076. doi: 10.3390/plants13152076.
This study explores the chemical composition of essential oils from two Serbian species (Apiaceae), L. and L., traditionally recognized in Chinese medicine for their therapeutic potential but less studied for their essential oils. Through GC-MS analysis, we identified 230 constituents, revealing distinct profiles between the species. Perillyl 2-methylbutanoate was identified in oil for the first time, confirmed using synthetic approaches and characterized by advanced spectroscopic techniques, including two-dimensional NMR and spin-simulation of H NMR spectra. Additionally, new natural compounds, including tentatively identified 4-decyl acetate and 4-undecyl acetate, were discovered. The study also reports five stereoisomeric esters of tetradeca-5,7,9,11-tetraen-1-ol. These findings significantly contribute to the understanding of the phytochemical diversity within the genus and underscore potential differences in ecological adaptations or biosynthetic pathways among species.
本研究探索了两种塞尔维亚伞形科植物（L.和L.）精油的化学成分，这两种植物在传统中医中因其治疗潜力而闻名，但对其精油的研究较少。通过气相色谱-质谱联用（GC-MS）分析，我们鉴定出230种成分，揭示了这两个物种之间不同的成分谱。首次在L.精油中鉴定出紫苏基2-甲基丁酸酯，通过合成方法进行了确认，并采用先进的光谱技术进行了表征，包括二维核磁共振（NMR）和氢核磁共振（H NMR）光谱的自旋模拟。此外，还发现了新的天然化合物，包括初步鉴定的4-癸基乙酸酯和4-十一烷基乙酸酯。该研究还报道了十四碳-5,7,9,11-四烯-1-醇的五种立体异构酯。这些发现对理解该属植物的植物化学多样性有显著贡献，并强调了物种间生态适应性或生物合成途径的潜在差异。
